Toxicity sentence example
Multiple sclerosis is not a death sentence, where methanol toxicity is.
Some foods hold varying levels of toxicity for your pet.
Cancer vaccines are currently being developed to confer active, specific immunotherapy directed against tumor-associated antigens, while inducing minimal systemic toxicity.
The ability to predict human or environmental toxicity without recourse to animal or tissue experiments seems very limited at the moment.
Studies in animals have shown reproductive toxicity including fetal malformations (see section 5.3 ).Advertisement
Normal doses in the severely malnourished may lead to toxicity.
They stated, " There is no way to reduce the toxicity of depleted uranium munitions.
Preliminary data indicate that stress can increase lithium pilocarpine toxicity in rats.
Differences in the constitution of the liposome can greatly affect the pharmacokinetic profile resulting in different patterns of toxicity.
Juvenile animals presented similar toxicity profiles to mature animals although enhanced nephrotoxicity in neonatal rats has been reported in some studies.Advertisement
The use of methotrexate high-dose regimens recommended for osteosarcoma requires meticulous care due to the potential for additive or synergistic renal toxicity.
The multiple sclerosis is not a death sentence, where methanol toxicity is.
With antidepressants, the only aspect of behavioral toxicity to have been formally investigated is excessive sedation in the short-term.
Except for transient thrombocytopenia in two patients there was no toxicity.
Recent research work has been directed at the toxicity associated with the levo isomer, and how it compares with the racemic preparation.Advertisement
A significant rebound flare in disease activity as the dose is tapered may prevent steroid withdrawal, resulting in concerns about long-term toxicity.
Reproduction toxicity studies are conducted to provide information concerning the effects of the test substance from the time of mating through to young adult.
Studies in animals have shown reproductive toxicity associated with maternal toxicity.
Liver toxicity Azathioprine, methotrexate, sulphasalazine and leflunomide can all regularly cause liver problems, which are reversible if the drug is discontinued.
Patients under 10 years and over 70 have increased risk of salicylate toxicity, and may require dialysis at an earlier stage.Advertisement
Not a single case of selenium toxicity was reported in any of the patients studied.
Probable toxicity of surface-active agent in commercial herbicide containing glyphosate.
Teratology studies in rats and rabbits showed maternal toxicity at high dose levels, but there was no evidence of embryotoxic or teratogenic potential.
The toxicity of chocolate for dogs is due to its theobromine content.
If toxicity is a problem, remove the transfection mixture and replace with normal medium.Advertisement
They inhibit the uricosuric effect of probenecid and may increase the toxicity of sulphonamides.
It has low toxicity, and can help regulate the thymus gland.
The actual theory behind the toxicity of clay litters does seem scientific.
The oil from the tea tree is nearly 13 times more powerful than carbolic acid without the toxicity and poisonous potency.
Directly ingesting the compound also increases the risk of toxicity.Advertisement
There are so many studies and so much research proving the toxicity of cooked food and the benefits of raw that can't be put in a small article.
The preliminary report from the Los Angeles county coroner's office is revealing that Murphy died from complications from pneumonia, anemia and prescription drug toxicity.
Toxicity test results revealed that there were no illegal drugs in Casey Johnson's system at the time of her death.
Two Minute Dog Advice columnist Wendy Nan Rees shares information on toxicity in pet products to help you keep your dog safe.
The relative toxicity of the bite is disputed, but it may induce a similar reaction to that of the brown recluse spider.Advertisement
Eating only liver can result in vitamin A toxicity.
The U.S. Environmental Protection Agency warns consumers not to use dog flea and tick products on cats because of the toxicity of permethrin and other ingredients harmful to cats.
Plastic may seem simple enough, but in order to prevent snapping and stability, Dirty Dog plastic frames are manufactured using TR90 which has no known problems of allergy and toxicity.
Although the drug is well tolerated in normal doses, it may have significant toxicity at high doses.
Infants are only given antacids in limited doses because of the risk of aluminum toxicity.Advertisement
The term mineral toxicity refers to a condition in which the concentration in the body of any one of the minerals necessary for life is abnormally high, and which has an adverse effect on health.
In general, mineral toxicity results when a person accidentally consumes too much of any mineral, as with drinking ocean water (sodium toxicity), or is overexposed to industrial pollutants, household chemicals, or certain drugs.
Mineral toxicity may also refer to toxic conditions resulting from certain diseases or injuries.
For example, a disorder known as hemochromatosis leads to iron toxicity, while Wilson's disease results in copper toxicity.
Severe trauma can lead to hyperkalemia or potassium toxicity.Advertisement
Iron poisoning is the most common form of mineral toxicity in children in the United States and is one of the leading causes of fatal poisoning in children younger than six years of age.
Death due to sodium toxicity has also resulted when baking soda (sodium bicarbonate) was used to treat excessive diarrhea or vomiting.
Although a variety of processed foods contain high levels of sodium chloride, the levels in these items are not enough to result in sodium toxicity.
In addition to goiter, iodine toxicity produces a brassy taste in the mouth, excessive production of saliva, and ulcers on the skin.
Iodine toxicity occurs fairly frequently in Japan, where people consume large amounts of seaweed.Advertisement
Within six hours of ingestion, iron toxicity can result in vomiting, diarrhea, abdominal pain, seizures, and possibly coma.
Calcium toxicity is rare, but overconsumption of calcium supplements may lead to deposits of calcium phosphate in the soft tissues of the body.
Phosphate toxicity can result from the overuse of laxatives or enemas that contain phosphate.
Severe phosphate toxicity can result in hypocalcemia and in various symptoms resulting from low plasma calcium levels.
Moderate phosphate toxicity occurring over a period of months may result in the deposit of calcium phosphate crystals in various tissues of the body.
A few instances of zinc toxicity have been reported in people who consumed acidic food or beverages that had been stored in galvanized zinc containers.
Early signs of selenium toxicity include nausea, weakness, and diarrhea.
Manganese toxicity in miners has been documented in Chile, India, Japan, Mexico, and elsewhere.
The most common form of mineral toxicity for children and adolescents in the United States is accidental poisoning from iron supplements.
An initial diagnosis of mineral toxicity requires taking a careful history.
Iron toxicity is treated by efforts to remove the remaining iron from the stomach by administering a solution of 5 percent sodium bicarbonate.
Treatment of manganese toxicity involves removal of the patient from the high manganese environment as well as giving him or her lifelong doses of the drug L-dopa.
Treatment of nitrite or nitrate toxicity involves inhalation of 100 percent oxygen for several hours.
Families consuming a well-balanced diet without overuse of dietary supplements are unlikely to have problems with mineral toxicity.
The prognosis for mineral toxicity due to sodium, potassium, calcium, and phosphate is usually excellent.
Toxicity due to the deposit of calcium phosphate crystals is not usually reversible.
The prognosis for treating iodine toxicity is excellent.
For any mineral toxicity that causes nerve damage, the prognosis is often fair to poor.
When mineral toxicity results from the excessive consumption of mineral supplements, toxicity can be prevented by minimizing the use of dietary supplements and keeping iron tablets in particular out of the reach of children.
Zinc toxicity may be prevented by not storing food or beverages in zinc containers.
In the case of iodine, toxicity can be prevented by avoiding overconsumption of seaweed or kelp.
In the case of selenium toxicity resulting from high-selenium soils, toxicity can be prevented by relying on food and water acquired from a low-selenium region.
Parental concerns about mineral toxicity in most children should be directed toward preventing accidental consumption of iron and other mineral supplements in young children and in monitoring the adoption of fad diets in teenagers.
Retardation can also be caused by damage to the fetus during pregnancy due to alcohol, drug abuse or toxicity, and disorders of the developing nervous system such as hydrocephalus.
Cadmium toxicity is generally indicated when urine levels exceed 10 mg/dL of creatinine and blood levels exceed 5 mg/dL.
Long-term use can produce toxicity so potent drugs, such as methotrexate (MTX) and cyclosporine, are not used with children.
Graudins, A., et al. "Red-back spider (Latrodectus hasselti) antivenom prevents the toxicity of widow spider venoms."
Signs of desferoxamine toxicity are screened for and generally develop in individuals who overuse the medication when body iron levels are sufficiently low.
Common underlying disorders include leukemia, drug toxicity, or aplastic anemia, all of which lead to decreased or defective production of platelets in the bone marrow.
Best effects and lowest toxicity are achieved when the blood levels of these drugs are kept constant.
It is never diagnosed before two years of age and is diagnosed only after drug toxicity and other primary immune deficiencies have been ruled out.
Owing to toxicity over the long term, some drugs can only be used for acute pain or as adjuncts in chronic pain management.
Other side effects include dry mouth, constipation, difficulty urinating, blurred vision, sedation, weight gain, central nervous system and cardiovascular toxicity, delirium, and risk of suicide by overdose.
The opposite condition, microcephaly, may be caused by failure of the brain to develop or by intrauterine infection, drug toxicity, or brain trauma.
If the nystagmus is due to drug toxicity, then reducing or discontinuing the drug eventually resolves the problem.
Some drugs in this class may cause kidney toxicity.
During the first seven days of the infant's life, TBS results are rated for risk of bilirubin toxicity or bilirubinrelated brain damage within percentile ranges representing degrees of hyperbilirubinemia.
Symptoms of toxicity are nausea, vomiting, pain in the joints, and lack of interest in eating food.
In adults, vitamin D toxicity occurs with eating 50,000 IU or more per day.
In infants, toxicity occurs with 1,000 IU per day.
Nutritional, botanical, and homeopathic medicines can be administered once the source is removed to help correct any imbalances brought on by lead toxicity.
Fat soluble vitamins remain in your body and can build up toxicity.
Vitamin B12 is a popular supplement with dosages often ranging into thousands of percent of RDA, so it's only natural to wonder about the potential for vitamin B12 toxicity.
Even when injected directly into the body, it seems vitamin B12 toxicity is something of a non-issue.
When high doses of vitamin B12 are given orally, only a small percentage can be absorbed, which may explain the low toxicity."
Many respected institutes like University of Pittsburgh Medical Center simply conclude that "No symptoms of vitamin B12 toxicity have been reported."
What does Uncle Sam have to say on the topic of vitamin B12 toxicity?
When the RDA guidelines received their major overhaul in 1998, the Board concluded the risk of toxicity was so low they simply chose not to establish an "upper limit" recommendation (1).
While it should be clearly established that vitamin B12 toxicity in and by itself is not a big risk, there are other concerns that should be mentioned.
Vitamin A is essential to our survival, so how can there be such a thing as vitamin A toxicity?
The severity of vitamin A toxicity depends on a lot of factors, such as body size and pre-existing conditions.
Vitamin D toxicity in the human body is a real prospect and may cause significant health problems when it is left untreated.
However, many Americans and doctors shy away from taking vitamin D for fear that they will cause toxicity.
The first thing you need to know about vitamin D toxicity is that it's harder to get than most people think.
Several years ago, scientists thought that any amount over the recommended levels of vitamin D would result in toxicity.
Excessive amounts to vitamin D, however, will cause toxicity.
There are a few important aspects about toxicity and vitamin D that you need to know.
First, a toxicity of vitamin D cannot be caused by prolonged and unprotected sun exposure.
Sun exposure is one of the best ways to get vitamin D into your system and it cannot cause any sort of toxicity.
So if you're taking vitamin D supplements, watch your body for any symptoms of toxicity.
You will likely not experience any adverse effects if you quickly stop taking vitamin D when symptoms of toxicity first appear.
Toxicity is impossible from sun exposure and unlikely from food sources.
Toxicity is far more likely to occur from taking vitamin D supplements or large amounts of cod liver oil.
Due to its toxicity, the FDA has banned synthetic vitamin K from over-the-counter supplements.
In some cases, it is possible to build up vitamin D toxicity if you are taking high levels of fish liver oil, or combining fish liver oil supplementation with vitamin D supplementation.
Check with your doctor, and be aware of signs of vitamin D toxicity if you are taking a fish liver oil.
While vitamin D toxicity is rare, all fat soluble vitamins have the potential to build up to toxic levels in your body.
Eating foods high in vitamin E as opposed to supplementation can help you avoid unhealthy buildup of vitamin E or vitamin E toxicity.
Because there is potential for vitamin A toxicity, it's always best to discuss supplementation with your personal health care provider.
The best way to get adequate nutrition and avoid toxicity - not just for vitamin A, but for all nutrients - is to eat a balanced diet containing a wide variety of whole foods.
Because of its potential toxicity, do not take more than one vitamin A-containing supplement at a time to prevent overdosing.
As one of four fat-soluble vitamins, vitamin E can build up in the body and lead to toxicity or overdose.
However, carefully monitoring dosage of supplementation of fat-soluble vitamins can help to prevent toxicity and overdose.
Overdose usually occurs when an extremely large amount of vitamin E is ingested at once, and vitamin E toxicity occurs when large amounts of vitamin E are taken over an extended period of time.
You will often find the terms overdose and toxicity used interchangeably, although there is a subtle difference between the two.
If you stay within these guidelines, it is highly unlikely you will ever experience toxicity or overdose of this vitamin.
If you are taking large doses of vitamin E and you experience any of the following symptoms, then you may be experiencing vitamin E toxicity or overdose.
If you suspect overdose or toxicity, see your doctor right away.
If you suspect overdose or toxicity of vitamin E, contact your personal health care provider immediately.
However, since no case of toxicity has ever been reported, taking a biotin supplement is considered to be safe.
Overdose or toxicity caused by the ingestion of too many B vitamins is thought to be nonexistent because the body simply excretes any excess of the water soluble vitamins via the urine.
Currently, there has never been a documented case of biotin toxicity.
Vitamins A, D and E are all fat-soluble vitamins that can build up toxicity, so working with your doctor is essential if you are taking these supplements.
Vitamin B can build up to toxic levels, leading to nerve pain and twitching, so it is important that you carefully monitor vitamin B intake and are aware of the signs of toxicity.
One of the concerns parents have when it comes to administering individual vitamins outside of a multi-vitamin is toxicity.
While vitamin C is water soluble, it can have certain toxicity associated with it.
Toxicity typically presents as gastrointestinal disorders - usually diarrhea and cramping.
If you are currently taking fish oil or cod liver oil, check with your doctor before adding vitamin D supplements into the mix, or toxicity could result.
Too much vitamin D through toxicity or an overdose can cause the body to experience high levels of blood calcium, which can then be deposited in the heart and lungs, reducing their functioning and endangering an individual's health.
They have also established an upper limit (UL), above which toxicity may result.
Instead, your body stores them, and excess amounts can build up toxicity.
Consuming your vitamins in foods rather than supplements can help avoid toxicity.
You may experience side effects due to the release of toxicity.
Additionally, it helps fight cancer because it attacks certain types of bile acid and reduces their toxicity.
It's also one of three ingredients - the others are toluene and phthalates - that are recognized by California's Proposition 65 as "known to cause cancer or developmental toxicity."
Despite this, there is still great concern over the risk of potential toxicity stemming from aluminum.
The toxicity or relative strength of the cobra venom has been calculated to be sixteen times that of the European viper.
However toxicity (including alopecia) is less than might be expected and in combination with pulse steroids cyclophosphamide is often well tolerated.
These mice provide an important animal model for study of the branched-chain amino acids metabolism and its toxicity.
Harmful toxic chemicals are minimized in manufacture through the Ecoplus System's use of low toxicity boron timber preservatives and natural oil-based timber finishes.
Remember that many patients have low serum creatinine initially therefore a good guide to toxicity is a doubling of the initial creatinine.
Perhaps the most severe and potentially deadly of the limitations is CNS oxygen toxicity.
The majority of transaminase elevations were of Grade 1-3 toxicity and resolved upon discontinuation of treatment.
Insoluble iron and iron compounds are low in toxicity, so the results strongly indicate that the nanotubes themselves induced the granulomas.
A review of vitamin E toxicity studies concluded that humans show few side effects following supplemental doses less.. .
Symptoms that may indicate the diagnosis include unexplained severe pain that increases rapidly over time associated with systemic toxicity including hypotension.
Severe toxicity is frequently accompanied by convulsions, which may also aggravate the potential for heart toxicity by inducing hypoxia.
Toxicity included leukopenia (8 patients) and thrombocytopenia (7 patients ).
Targeted molecular therapy, although as of 2004 still the subject of concentrated research, was being used effectively in pediatric study subjects where it has been shown to reduce the toxicity seen with conventional chemotherapy.
With regard to diseases leading to mineral toxicity, about one person in ten in the United States has the genetic mutation that can lead to hemochromatosis; however, not everyone with this mutation necessarily develops the disease.
If, for example, the brain and spinal cord removed from an animal be bruised and brought into contact with tetanus toxin, a certain amount of the toxicity disappears, as shown by injecting the mixture into another animal.