The telethon is set to air September 5, 2008 on NBC and CBS.
In the past, the actress has help to raise millions of dollars by acting as the Lee National Denim Day spokesperson and presently, she has a planned appearance with other stars on the Stand Up to Cancer telethon.
Sweeney has co-hosted the annual Jerry Lewis Labor Day Telethon to raise funds to fight Muscular Dystrophy three times, from 2007-2009.
She has co-hosted a segment of the annual Jerry Lewis Telethon, which raises money and awareness for Muscular Dystrophy.
You can work the phone lines at a telethon, walk dogs at the animal shelter, package food at a food bank, and much more.