T-cells Sentence Examples
However, T cells do not recognize many tumor antigens directly on the cells.
However, so far it has not been proven by sequence analysis that the cultured T cells truly represent the malignant cells.
Rheumatoid arthritis synovial T cells regulate transcription of several genes associated with antigen-induced anergy.
Enhanced proliferation of CD4+ T cells induced by dendritic cells following antigen uptake in the presence of antibody.
All of them are derived from the bone marrow but T cells undergo a process of maturation in the thymus gland.
This treatment, called antigen-specific immunotherapy, specifically targets the immune system's T cells that cause the disease.
Our findings indicate the importance of combining engineered T cells with other anti-tumour strategies such as vaccination to achieve a better tumor immunotherapy.
If human T cells could also be made insensitive to TGF-beta signals, then these findings could be adapted to treat cancer patients.
In the presence of Tregs, there is decreased infiltration of pathogenic T cells into the pancreatic islets.
Plays a role in negative selection of developing T cells and the killing of targets by cytotoxic T lymphocytes.Advertisement
In addition to the decline of certain subpopulations of T cells, important changes occur at the cell surface of all T cells.
In short, CTCL may be a malignancy of T cells stimulated to proliferate against its own tumor antigens.
Immunotherapy uses the body's own immune system, specifically a type of disease-fighting white cell called T-cells, to destroy cancer cells.
The T cells protect the body against viruses.
The T cells recognize these proteins and make certain chemicals that are capable of destroying the virus-infected cells.Advertisement
In addition, the T cells can destroy some types of cancer cells.
The two main groups are the B cells that have antibody molecules on their surface and T cells that destroy antigens.
T-cells are few and weak, and the thymus gland is immature.
In all forms of SCID, B and T cells are non-functioning.
As an example of gene therapy for SCID children with ADA deficiency, the child receives periodic infusions of his or her own T cells corrected with a gene for ADA that has been implanted in an activated virus.Advertisement
Children with an ADA deficiency have low levels of both B and T cells.
When introduced into the body, the antigens stimulate the immune system response by instructing B cells to produce antibodies, with assistance from T-cells.
When new antigens enter the body, white blood cells (called macrophages) engulf them, process the information contained in the antigens, and send it to the T-cells so that an immune system response can be mobilized.
The T cells can recognize these proteins and produce certain chemicals (cytokines) that are capable of destroying the virus-infected cells.
Hyper-IgM syndrome is caused by a mutation in a gene on the X chromosome that affects the patient's T cells.Advertisement
Normal T cells produce a ligand (a small molecule that links to larger molecules) known as CD40.
In one Japanese study, five out of seven patients who received BMT survived, with four of the five producing T cells with normal CD40 ligand without supplementary IVIG therapy.
Hyper-IgM syndrome is caused by a lack of a ligand known as CD40 on the surfaces of the T cells in the child's blood.
When exposed to the allergen, the T-cells are activated and cause an inflammatory response.
Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS) by infecting helper T cells of the immune system.
These drugs interrupt the virus replication cycle and, therefore, spare the T cells.
If medical treatment is timely and successful, T cells do not become depleted and opportunistic infections do not occur.
The immune system of patients with WAS produces too few B and T cells.
Both B and T cells are needed to defend the body against infection.
About 50 percent of individuals with WAS are helped by treatment with transfer factor, which is a substance derived from the T cells of a healthy person.