T-cells Sentence Examples
- However, T cells do not recognize many tumor antigens directly on the cells. 
- However, so far it has not been proven by sequence analysis that the cultured T cells truly represent the malignant cells. 
- Rheumatoid arthritis synovial T cells regulate transcription of several genes associated with antigen-induced anergy. 
- Enhanced proliferation of CD4+ T cells induced by dendritic cells following antigen uptake in the presence of antibody. 
- All of them are derived from the bone marrow but T cells undergo a process of maturation in the thymus gland. 
- This treatment, called antigen-specific immunotherapy, specifically targets the immune system's T cells that cause the disease. 
- Our findings indicate the importance of combining engineered T cells with other anti-tumour strategies such as vaccination to achieve a better tumor immunotherapy. 
- If human T cells could also be made insensitive to TGF-beta signals, then these findings could be adapted to treat cancer patients. 
- In the presence of Tregs, there is decreased infiltration of pathogenic T cells into the pancreatic islets. 
- Plays a role in negative selection of developing T cells and the killing of targets by cytotoxic T lymphocytes. Advertisement
- In addition to the decline of certain subpopulations of T cells, important changes occur at the cell surface of all T cells. 
- In short, CTCL may be a malignancy of T cells stimulated to proliferate against its own tumor antigens. 
- Immunotherapy uses the body's own immune system, specifically a type of disease-fighting white cell called T-cells, to destroy cancer cells. 
- The T cells protect the body against viruses. 
- The T cells recognize these proteins and make certain chemicals that are capable of destroying the virus-infected cells. Advertisement
- In addition, the T cells can destroy some types of cancer cells. 
- The two main groups are the B cells that have antibody molecules on their surface and T cells that destroy antigens. 
- T-cells are few and weak, and the thymus gland is immature. 
- In all forms of SCID, B and T cells are non-functioning. 
- As an example of gene therapy for SCID children with ADA deficiency, the child receives periodic infusions of his or her own T cells corrected with a gene for ADA that has been implanted in an activated virus. Advertisement
- Children with an ADA deficiency have low levels of both B and T cells. 
- When introduced into the body, the antigens stimulate the immune system response by instructing B cells to produce antibodies, with assistance from T-cells. 
- When new antigens enter the body, white blood cells (called macrophages) engulf them, process the information contained in the antigens, and send it to the T-cells so that an immune system response can be mobilized. 
- The T cells can recognize these proteins and produce certain chemicals (cytokines) that are capable of destroying the virus-infected cells. 
- Hyper-IgM syndrome is caused by a mutation in a gene on the X chromosome that affects the patient's T cells. Advertisement
- Normal T cells produce a ligand (a small molecule that links to larger molecules) known as CD40. 
- In one Japanese study, five out of seven patients who received BMT survived, with four of the five producing T cells with normal CD40 ligand without supplementary IVIG therapy. 
- Hyper-IgM syndrome is caused by a lack of a ligand known as CD40 on the surfaces of the T cells in the child's blood. 
- When exposed to the allergen, the T-cells are activated and cause an inflammatory response. 
- Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS) by infecting helper T cells of the immune system. 
- These drugs interrupt the virus replication cycle and, therefore, spare the T cells. 
- If medical treatment is timely and successful, T cells do not become depleted and opportunistic infections do not occur. 
- The immune system of patients with WAS produces too few B and T cells. 
- Both B and T cells are needed to defend the body against infection. 
- About 50 percent of individuals with WAS are helped by treatment with transfer factor, which is a substance derived from the T cells of a healthy person.