perforate the bowel wall, leaving the submucosa and muscle layers intact.
The walls of the GI tract have four layers of tissue, called mucosa, submucosa, muscularis externa, and serosa.
Connective tissue and muscle separate the muscosa from the second layer, the submucosa, which contains blood vessels, lymph vessels, nerves, and glands.
Next to the submucosa is the muscularis externa, consisting of two layers of muscle fibers, one that runs lengthwise and one that encircles the bowel.
Pattern I eosinophilic gastroenteritis: Children affected with Pattern I EG have extensive infiltration of eosinophils in the area below the submucosa and muscularis layers.
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