While about 50 percent of children diagnosed with JDMS have an acute onset of symptoms, the other 50 percent have what is called a subacute onset, which means that the symptoms are milder and come on more slowly.
While most children with acute symptoms are diagnosed within three months, the correct diagnosis of children with subacute symptoms may take a year or even longer.
This interval is sometimes more prolonged particularly if the initial infection was treated with antibiotics but not completely eliminated (subacute mastoiditis).
Subacute lesions: These are characterized by reddening, peeling, and scaling but are less severe than acute lesions and do not produce an exudate.
Called subacute sclerosing panencephalitis, this is a slowly progressing, smoldering swelling and destruction of the entire brain.
Subacute mastoiditis refers to a more chronic disease, often following partial treatment of AOM with antibiotics.
In subacute and chronic Bright's disease, lead poisoning and other obscure conditions.
Salts of silver are most useful as an injection in subacute and chronic gonorrhoea, either the nitrate (I to 5% solution) being employed, or protargol, which is a proteid compound containing 8% of silver nitrate, is used in 1% solution; they also benefit in leucorrhoea.
Though ammonium chloride has certain irritant properties which may disorder the stomach, yet if its mucous membrane be depressed and atonic the drug may improve its condition, and it has been used with success in gastric and intestinal catarrhs of a subacute type and is given in doses of io grains half an hour before meals in painful dyspepsia due to hyperacidity.
(Many such changes are usually grouped together under the heading of " inflammation " of varying degree--acute, subacute and chronic.) Degeneration and death of cells, haemorrhages, serous and fibrinous exudations, leucocyte emigration, proliferation of connective tissue and other cells, may be mentioned as some of the fundamental changes.