Strychnine Sentence Examples
Alcohol, strychnine and warmth must also be employed.
As in strychnine poisoning, the patient is conscious and clear-minded to the last.
A species of Acarus is recorded as infesting a store of powdered strychnine and feeding on that drug, so poisonous to larger organisms. Reference to literature (40).
It is very similar to strychnine, both chemically and physiologically.
Fraser proved that by substitution of molecules in certain compounds a stimulant could be converted into a sedative action; thus by the addition of the methyl group CH 2 to the molecule of strychnine, thebaine or brucine, the tetanizing action of these drugs is converted into a paralysing action.
Also (d +1) mannonic acid can be split into the d and 1 acids by fractional crystallization of the strychnine or brucine salts.
In this case stimulants and strychnine may be given, but they should be avoided until it is certain the bleeding has been properly controlled, as they tend to increase it.
Small, stimulating doses, and repeated, are good, but stimulation can be more effectively produced by ammonia or strychnine.
Hypodermic injection of strychnine, in some cases as much as one to two grains (but not into a vein!), has in some cases had good results; but injection of ammonia, instead of doing any good, has disastrous sloughing results.
Piperine, conine, atropine, belladonine, cocaine, hyoscyamine and nicotine have been already synthesized; the constitution of several others requires confirmation, while there remain many important alkaloids - quinine, morphine, strychnine, &c. - whose constitution remains unknown.
AdvertisementIt is precisely the reverse of the typical action of strychnine.
Strychnine crystallizes from alcohol in colourless prisms, which are practically insoluble in water, and with difficulty soluble in the common organic solvents.
Brucine closely resembles strychnine, and is its dimethoxy derivative.
The B.P. dose of strychnine is to gr.
Strychninae hydrochloridum is also used; it is much more soluble than strychnine.
AdvertisementStrychnine is incompatible with liquor arsenicalis and potassium iodide.
Applied externally strychnine is a powerful antiseptic, but its poisonous nature prevents it from being used for this purpose.
Brucine is a local anaesthetic. Strychnine enters the blood as such, being freely absorbed from mucous surfaces or when given hypodermically.
Internally strychnine acts as a bitter, increasing the secretion of gastric juice and the intestinal peristalsis, being a direct stimulant to the muscular coat; in this manner it has a purgative action.
Strychnine is eliminated by the kidneys as strychnine and strychnic acid.
AdvertisementStrychnine is chiefly used as a stimulant.
In pneumonia and other acute disease, where the patient is liable to sudden collapse, a hypodermic injection of strychnine will often save the patient's life.
In acute opium poisoning strychnine is very valuable.
In dyspnoea due to emphysema, phthisis and asthma, strychnine is of service, given internally in doses of i to 3 minims of the liquor.
The syrup of iron, quinine and strychnine is used as a tonic.
AdvertisementThe symptoms of strychnine poisoning usually appear within twenty minutes of the ingestion of a poisonous dose, starting with an uneasy sensation, stiffness at the back of the neck, twitching of the muscles and a feeling of impending suffocation.
Tetanus resembles strychnine poisoning, but the development of the symptoms in tetanus is usually much slower, death rarely occurring within 24 hours.
In strychnine poisoning trismus or lockjaw is generally secondary to spasm of the other muscles, while in tetanus it is usually the first symptom, no relaxation taking place between the spasms.
The treatment of strychnine poisoning is to immediately evacuate the stomach with a stomach-pump or emetic, chloroform being administered to allay the spasms. If the patient can swallow, draughts of water containing tannic acid may be given.
This is indeed, as Sir Thomas Fraser has pointed out, "a strychnine action."
It is to be noted that children, who are particularly susceptible to the influence of certain of the other potent alkaloids, such as morphine and strychnine, will take relatively large doses of atropine without ill-effect.
When the nervous system is below par, and both secretion and movements are deficient in the stomach, nervine tonics, such as nux vomica or strychnine, are most useful.
In such cases nux vomica or strychnine is useful.
Of the other alkaloids narceine is hypnotic, like morphine and codeine, whilst thebaine, papaverine and narcotine have an action which resembles that of strychnine, and is, generally speaking, undesirable or dangerous if at all well marked.
In infants especially opium acts markedly upon the spinal cord, and, just as strychnine is dangerous when given to young children, so opium, because of the strychnine-like alkaloid it contains, should never be administered, under any circumstances or in any dose, to children under one year of age.
Crum Brown and Fraser of Edinburgh showed that, whilst thebaine acts like strychnine, methyl and ethyl thebaine act like curara, paralysing the terminals of motor nerves.
The conditions in which bromides are most frequently used are insomnia, epilepsy, whooping-cough, delirium tremens, asthma, migraine, laryngismus stridulus, the symptoms often attendant upon the climacteric in women, hysteria, neuralgia, certain nervous disorders of the heart, strychnine poisoning, nymphomania and spermatorrhoea.
The collapse must be treated with hot blankets and bottles, and subcutaneous injections of brandy, ether or strychnine.
The effects of many of these toxins bear a close resemblance to the action of certain wellknown drugs, as in the case of tetanus toxin and strychnine, and are studied by the same methods of observation and research.
The action of a drug may be called direct when it acts on any part to which it is immediately applied, or which it may reach through the blood; and indirect when one organ is affected secondarily to another, as, for instance, in strychnine poisoning when the muscles are violently contracted as the result of the action of the alkaloid upon the spinal cord.
Certain substances, notably digitalis, lead, mercury and strychnine, exhibit what is called a cumulative action - that is to say, when small quantities have been taken over a period of time, poisoning or an excessive action suddenly ensues.
Thus curare may stop strychnine convulsions by paralysing the terminations of motor nerves, and chloroform may exercise the same effect by abolishing the irritability of the spinal cord.
In morphine, on the higher animals at least, the narcotic action is very marked, the tetanizing action slightly so; while in thebaine there is little narcotic effect, but a tetanizing action like that of strychnine.
Strychnine and brucine very closely resemble each other in action, and under this heading curarine may also be included.
Depending on demand we may issue permits to use strychnine up to 1 August 2006.
To allow time for processing, all applications to purchase strychnine must be received by the departments by 28 April 2006.
There's not enough space on a LSD blotter to contain enough strychnine to poison you.
So we cannot work with any company to take strychnine off the market.
There is still time to support strychnine under the Biocidal Products Directive.
In his testimony he gave Palmer an alibi for the time when Newton claimed that Palmer had bought strychnine.
Now that the poison strychnine is to be banned for use by licensed trappers the problem will be even greater.
There 's not enough space on a LSD blotter to contain enough strychnine to poison you.
Defra and the agriculture departments in Scotland and Wales now issue permits for purchase and use of strychnine hydrochloride only for biocidal purposes.
The symptoms of death were regarded as being consistent with strychnine poisoning.
Strychnine blocks glycine receptors in the brain, causing muscle convulsions and death.
Impurities or additives, which make the heroin darker, can include things like sugar, starch, powdered milk, strychnine, other poisons and more drugs.
Additives include sugar, starch, powdered milk, strychnine, quinine, and other poisons or drugs.
Yet another group, including cocaine, ergot, strychnine, and some snake venoms, causes potentially fatal seizures.
Possible causes include stroke, multiple sclerosis, cerebral palsy, neurodegenerative diseases, trauma, spinal cord injury, and nervous system poisons such as strychnine, tetanus, and certain insecticides.
No certain cure has been or is likely to be discovered for their poison, but in less serious cases strychnine has been used with advantage.