These include SMA type I, also called Werdnig-Hoffmann; SMA type II; SMA type III, also called Kugelberg-Welander disease; Kennedy syndrome, or progressive spinobulbar muscular atrophy; and congenital SMA with arthrogryposis.
In general, when a family has already had a child with SMA, each subsequent pregnancy has a 25 percent chance of producing another child with SMA.
Parents must then decide whether to use the information to help them prepare for the arrival of a baby with SMA or to terminate the pregnancy.
Babies with this type of SMA have decreased muscle and trunk tone, resulting in floppiness of the limbs and weak arm and leg movements.
SMA type I is usually noted prior to birth, due to a decrease in the baby's movements in utero, or early in life.
Children with SMA type II may eventually be able to sit, but they are unable to learn to stand or to walk.
Parents of children with SMA usually carry the gene for the disease but have no symptoms themselves.
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The Great Lakes are peculiar in receiving the drainage of but a sma]l peripheral land area, enclosed by an ill-defined water-parting from the rivers that run to Hudson Bay or the Gulf of St Lawrence on the north and to the Gulf of Mexico on the south.
Sweden itself may be considered in four main physical divisions - the mountains and highland district, covering all Norrland and the western part of Svealand; the lowlands of central Sweden; the so-called Sma.land highlands, in the south and southeast; and the plains of Ska.ne, occupying the extreme southward projection of the peninsula.