Sickle cell sentence example
People with Sickle Cell Anemia often have mild jaundice which can make the whites of their eyes look yellowish.
This so-called "heterozygote advantage" is seen in some other genetic disorders, including sickle-cell anemia.
Individuals with sickle cell trait, although generally asymptomatic, can develop symptoms of sickling if exposed to very low oxygen pressures.
Patients with sickle cell disease are treated at The Royal London.
Objectives To assess the effects of routine malaria chemoprophylaxis in people with sickle cell disease.Advertisement
To achieve the lowest possible childhood death rate and to minimize childhood morbidity from sickle cell disorders.
Carriers of sickle Cell are sometimes said to have ' sickle cell trait ' .
Plain English Summary Antenatal screening for haemoglobinopathies (thalassaemia and sickle cell disease) has been available since the 1970s.
Carriers of Sickle Cell are sometimes said to have ' sickle cell trait '.
Back to top Why might I be tested for sickle cell anemia?Advertisement
The increased risk among African Americans is not explained by the presence of sickle cell disease, nor is the excess risk among boys explained by trauma.
The most common causes of stroke are congenital (present at birth) and acquired heart diseases, and sickle cell anemia.
About 10-15 percent of children with sickle cell disease suffer a stroke, usually ischemic stroke.
Blood transfusions may be used to treat children with sickle cell disease.
Although there is a high risk of repeat strokes in patients with sickle cell anemia, the risk can be reduced with regular blood transfusions.Advertisement
In addition, there is a blood test for fifth disease, but it is generally used only for pregnant women and for people who have weakened immune systems or who suffer from blood disorders, such as sickle cell anemia.
Sickle cell anemia, also called sickle cell disease (SS disease), is an inherited condition caused by having abnormal hemoglobin, the protein that carries oxygen in the blood.
People with sickle cell anaemia have sickle hemoglobin (HbS) which is different from the normal hemoglobin (HbA).
Children with sickle cell anemia produce two abnormal hemoglobin proteins (inheriting one from each parent), which makes their red blood cells easily destructible while giving them a sickle-like shape.
Sickle cell anemia is usually inherited from parents who are carriers, who have the sickle cell trait-a milder form of sickle cell anemia, or one abnormal hemoglobin.Advertisement
Sickle cell anemia and sickle cell trait are found mainly in people whose families come from Africa, the Caribbean, the Eastern Mediterranean, Middle East, and Asia.
In the United States, sickle cell anemia affects some 72,000 people.
Some 2 million Americans carry the sickle cell trait and about one in 12 African Americans have the trait.
Parents should know that a child having a sickle cell crisis requires urgent hospital treatment.
The diagnosis of sickle cell anemia is established during the newborn screen testing that is performed in the nursery at time of birth.Advertisement
For children who are not tested, an electrophoresis test of the blood can detect the abnormal hemoglobin of sickle cell anemia.
Children with sickle cell disorders are at risk of developing severe infections, and penicillin is usually prescribed to prevent dangerous pneumococcal infections.
Bone marrow transplantation has been shown to provide a cure for severely affected children with sickle cell disease, but the procedure is not entirely without risk.
In addition, the marrow must come from a healthy matched sibling donor and only about 18 percent of children with sickle cell anemia are likely to have a matched sibling.
Research contributed a great deal about sickle cell anemia from 1970 to the early 2000s concerning what causes it, how it affects the patient, and how to treat it.
Scientists were as of 2004 starting to be successful at developing drugs that prevent the symptoms of sickle cell anemia and procedures that they hope should eventually provide a cure.
It has been observed that some children with sickle cell anemia continue to produce large amounts of fetal hemoglobin after birth, and studies have shown that these children have less severe cases of the disease.
Children with sickle cell anemia are anemic to various degrees.
Both sickle cell trait and sickle cell anemia are inherited.
If one partner has sickle cell trait and the other does not, their children each have a 50 percent chance of having the sickle cell trait, and a 50 percent chance of having normal hemoglobin.
If one parent has sickle cell trait it is extremely important that the other parent be tested.
If both parents have sickle cell trait and want to know whether the unborn child has sickle cell anemia, testing can be performed as early as the tenth week of pregnancy.
Parents should be aware that children with sickle cell anemia are also at increased risk of infection, especially from the Streptococcus pneumonia and H. influenzae bacteria.
Children with sickle cell disorders can almost always attend school and participate fully in normal activities.
Sickle cell trait-Condition that occurs in people who have one of two possible genes responsible for the abnormal hemoglobin of sickle cell anemia.
People with this trait may suffer milder symptoms of sickle cell anemia or may have no symptoms.
J., et al. "Declining stroke rates in Californian children with sickle cell disease."
H. "Therapies to increase fetal hemoglobin in sickle cell disease."
A., et al. "Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease."
Sometimes bed-wetting can be caused by a serious medical problem like diabetes, sickle-cell anemia, or epilepsy.
Children older than five years do not need vaccination, unless the child or adolescent has a serious health problem that lowers immunity, such as HIV infection, sickle cell disease, or is being treated for cancer.
When capillaries become obstructed, a life-threatening condition called sickle cell crisis is likely to occur.
A child who inherits the sickle cell gene from each parent will have the disease.
A child who inherits the sickle cell gene from only one parent carries the sickle cell trait but does not have the disease.
Diagnosing thalassemia and sickle cell anemia, both of which involve disorders of hemoglobin, will require measuring the different types of hemoglobin through a laboratory testing method called hemoglobin electrophoresis.
Immunizations for pneumonia and infectious diseases are part of treatment along with prompt treatment for sickle cell crises and infections of any kind.
The hereditary anemias, such as the thalassemias and sickle cell anemia, may require life-long treatment and monitoring whereas other types of anemia, once treated, are apt not to recur.
Managing Sickle Cell Disease in Low-Income Families.
Fetal hemoglobin measurement helps diagnose a group of inherited disorders that affect hemoglobin production, among which are the thalassemias and sickle cell anemia.
For example, HbF can be found in higher levels in sickle cell anemia and other hereditary anemias.
By 1997, approximately 800 different diagnostic tests were available, most of them for hereditary genetic disorders such as Tay-Sachs disease, sickle cell anemia, hemophilia, muscular dystrophy, and cystic fibrosis.
Examples of genetic conditions include Down syndrome, Tay-Sach's disease, sickle cell disease, and hemophilia.
Severe diseases in the liver or kidneys, certain infections, sickle cell anemia, and some cancers also affect gonads.
Depending on your genetic background, you and your partner may also want to have a pregnancy blood test for genetic problems such as sickle cell disease or Tay-Sachs.
Blood donations benefit premature babies, cancer patients, individuals with sickle cell anemia and individuals undergoing surgery.