Figure 1. Brain stem centers damaged by the poliovirus involved in brain activation and blood pressure and heart rate regulation.
conceivable that such groups of individuals might also maintain the live vaccine strain of poliovirus.
postmortem histopathology from nearly fifty years ago demonstrated the consistent presence of poliovirus lesions in specific brain areas.
Ongoing surveillance in formerly endemic Central and South American countries confirms that poliovirus transmission remains interrupted.
Postmortem histopathology from nearly fifty years ago demonstrated the consistent presence of poliovirus lesions in specific brain areas.
It organized trials of poliovirus and measle vaccines and more recently the very successful combined measles, mumps and rubella (MMR) vaccine.
Acute Polio: Poliovirus invasion of one motor neuron produces degeneration of the motor neuron with denervation of muscle fibers innervated by that neuron.
Predisposition to motor neuron degeneration because of the glial, vascular, and lymphatic changes caused by poliovirus.
Up to now they had struggled to find the poliovirus in human spinal tissue.
He hoped our sensitive immune system would react by creating antibodies to these viral corpses that would also protect us against living wild poliovirus.
Complete nucleotide sequence of the attenuated poliovirus Sabin 1 strain genome.
Diseases of close association: In 1994, an international commission certified the eradication of endemic wild poliovirus from the Americas.
poliovirus lesions in specific brain areas.
poliovirus vaccine administrations in May and October.
poliovirus infection of the motor neuron.
poliovirus receptor in human spinal cord and muscle.
poliovirus strains in humans.
poliovirus type 2 Lansing.
There was an extensive epidemic of poliomyelitis in Iceland caused by type I poliovirus that coincided with and was followed by outbreaks of ID.
In 1908, the poliovirus was identified as the cause.
Crowded living conditions and poor hygiene encourage the spread of poliovirus.
Poliovirus can be spread by direct exposure to an infected individual, and more rarely, by eating foods contaminated with waste products from the intestines (feces) and/or droplets of moisture (saliva) from an infected person.
About 10 percent of people infected with poliovirus develop severe headache and pain and stiffness of the neck and back.
About 1 percent of people infected with poliovirus develop the most severe form.
When poliovirus invades the brainstem (the stalk of brain which connects the two cerebral hemispheres with the spinal cord, called bulbar polio), a person may begin to have trouble breathing and swallowing.
When poliovirus causes only the minor illness or simple aseptic meningitis, the patient can be expected to recover completely.
A vaccine takes advantage of the fact that infection with polio leads to an immune reaction, which will give the person permanent, lifelong immunity from reinfection with the form of poliovirus for which the person was vaccinated.
This immunization contains no live virus, just the components of the virus that provoke the recipient's immune system to react as if the recipient were actually infected with the poliovirus.
The recipient thus becomes immune to infection with the poliovirus.
It contains the live, but weakened, poliovirus and because OPV uses the live virus, it has the potential to cause infection in individuals with weak immune defenses (both in the person who receives the vaccine and in close contacts).
The coxsackie-virus and the poliovirus are both enteroviruses.
Avoiding the use of vaccines made from live viruses (measles, poliovirus, mumps, rubella).
Polio vaccine (IPV, or inactivated poliovirus vaccine)-This is usually given in a series of five vaccines, at ages two months, four months, six to 18 months, and four to six years.
The poliomyelitis (polio) vaccine protects against poliovirus infections.
There are two forms of the vaccine that can be given; the one preferred is the inactivated poliovirus vaccine (IPV).
Immunization from the IPV triggers an excellent immune response and long-lasting immunity to all three poliovirus types.
The inactivated poliovirus vaccine is injected into a muscle or under the skin and is usually given by a health care professional in a hospital, clinic, or provider's office.
Serious reactions to the inactivated poliovirus vaccine are rare in small children.
Children receiving the inactivated poliovirus vaccine should be carefully observed for 24-72 hours after receiving the injection.
If an individual is infected with the wild-type poliovirus, the virus can multiply in the intestines and be shed in stools, ultimately heightening the risk of viral circulation within the community.
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