Platelets Sentence Examples
It works by preventing the formation of a chemical called cyclic amp in blood platelets.
Now, 40% of adult therapeutic doses (ATD) of platelets collected by the NBS are collected by apheresis.
Platelets from men and women with diabetes are often hypersensitive in vitro to platelet aggregating agents.
The remaining platelets are then transfused back into the patient.
Platelets, apheresis means a concentrated suspension of blood platelets obtained by apheresis.Advertisement
What more could the NBS do to reduce the risk of bacterial contamination of platelets?
Donors might be especially called to a clinic to provide HLA class I matched platelets for a certain patient.
Images include basophils, monocytes, eosinophils neutrophils, lymphocytes, and platelets.
However, at presentation with relapse, she had received 2 units of red cells and 2 units of platelets which were not irradiated.
Occasionally, if an appropriate product is not available, it may be necessary to use RhD positive platelets.Advertisement
The recipient (58 year old male) suffered fatal septic shock after transfusion with a 2-day old unit of pooled platelets.
In patients dependent on platelet transfusion, HPA antibodies may be a cause of refractoriness to random donor platelets.
Alternatively selection of compatible platelets by crossmatching can be considered.
Rhesus D negative women of childbearing age should receive Rhesus D negative platelets.
The patient with AML was receiving multiple transfusions of both red cells and platelets, and thus presented as a case of platelet refractoriness.Advertisement
However, my blood platelets were not rising, nor were my liver enzymes decreasing.
In some patients with HLA antibodies, HPA antibodies may also be present requiring donor platelets matched for both type of antibodies.
Both Rams head and Spiral wedging involve the folding of the clay on itself too build up an ever tightening spiral of clay platelets.
Aspirin is sometimes used in children with heart conditions as it reduces the stickiness of the platelets in the blood.
Thrombin activation of the platelets was successful only when the concentration of the platelets was high enough.Advertisement
They inhibit blood clotting by blocking thromboxane formation in blood platelets.
The first few days ' blood tests showed high platelets, due to the many transfusions of platelets received during surgery.
Platelets are activated when an injury causes a blood vessel to break.
It is this aggregation of platelets which triggers the cascade of reactions leading to blood clot formation (thrombosis).
This recent microbiological research study gives new insight to the intracellular control mechanisms of platelets.Advertisement
Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder caused by an abnormally low level of blood platelets, small disc-shaped cells essential to blood clotting (coagulation).
Coagulation, or clotting, is a complex process in which specific proteins found in blood plasma combine with other blood components, including platelets, to form clots and prevent blood loss.
Platelets are tiny colorless disc-shaped cells in the blood that collect (aggregate) in blood vessels to form a plug when a vessel is injured.
A deficiency in platelets or a disorder that affects platelet production can disrupt clotting and severely complicate blood loss from accidental injury, surgery, and specific diseases or conditions in which bleeding can occur.
In adults, ITP is considered an autoimmune disorder, which means that the body produces antibodies that damage some of its own products-in this case, blood platelets.
In addition to physically plugging breaks in blood vessel walls, platelets also release chemicals that promote clotting.
Thrombocytopenia-A persistent decrease in the number of blood platelets usually associated with hemorrhaging.
This may include transfusions of platelets, intravenous immunoglobulins, or prednisone.
Prednisone is a steroid medication that decreases the effects of antibodies on platelets and eventually lowers antibody production.
Bone marrow-The spongy tissue inside the large bones in the body that is responsible for making the red blood cells, most white blood cells, and platelets.
Blood is made up of red blood cells (RBCs), which carry oxygen and other materials to all tissues of the body; white blood cells (WBCs), which fight infection; and platelets, which play a part in the clotting of the blood.
These stem cells mature through stages into RBCs, WBCs, or platelets.
This uncontrolled proliferation of the immature cells in the bone marrow affects the production of the normal red blood cells and platelets as well.
Low level of platelets (tiny cellular elements in blood that are an important part of coagulation).
Plasma-A watery fluid containing proteins, salts, and other substances that carries red blood cells, white blood cells, and platelets throughout the body.
Whole blood-Blood which contains red blood cells, white blood cells, and platelets in plasma.
A platelet count is a diagnostic test that determines the number of platelets in the patient's blood.
Platelets, which are also called thrombocytes, are small disk-shaped blood cells produced in the bone marrow and involved in the process of blood clotting.
There are normally between 150,000-450,000 platelets in each micro-liter of blood.
Low platelet counts or abnormally shaped platelets are associated with bleeding disorders.
This increase is caused by a change in the shape of the platelets after removal from the body.
This period is the best time to count the sample when using electronic instruments, because the platelets will be within a standard size range.
Platelets can be observed in a direct blood smear for approximate quantity and shape.
Accurate assessment of the number of platelets requires other methods of counting.
For a proper count, the platelets should be evenly distributed in the hemacytometer.
For these instruments to work properly, the sample must not contain other material that might mistakenly be counted as platelets.
Clumps of platelets will also not be counted.
In addition, if the patient has a high white blood cell count, electronic counting may yield an unusually low platelet count because white blood cells may filter out some of the platelets before the sample is counted.
On the other hand, if the red blood cells in the sample have burst, their fragments will be falsely counted as platelets.
Hemocytometer-An instrument used to count platelets or other blood cells.
It occurs in polycythemia vera and other disorders in which the bone marrow produces too many platelets.
The normal range for a platelet count is 150,000-450,000 platelets per microliter of blood.
An abnormally low platelet level (thrombocytopenia) is a condition that may result from increased destruction of platelets, decreased production, or increased usage of platelets.
In idiopathic thrombocytopenic purpura (ITP), platelets are destroyed at abnormally high rates.
Hypersplenism is characterized by the collection (sequestration) of platelets in the spleen.
Leukemia and aplastic anemia can result in a low platelet count because of decreased production of platelets in the bone marrow.
Abnormally high platelet levels (thrombocytosis) may indicate either a benign reaction to an infection, surgery, or certain medications; or a disease like polycythemia vera, in which the bone marrow produces too many platelets too quickly.
Serotonin-A widely distributed neurotransmitter that is found in blood platelets, the lining of the digestive tract, and the brain, and that works in combination with norepinephrine.
The infection may also cause significant destruction of the body's red blood cells or platelets.
These include anemia, or breakdown of red blood cells; reduced platelets; reduced white cells; and bone marrow failure.
Anticoagulant drugs inhibit clot formation by blocking the action of clotting factors or platelets.
Antiplatelet drug-Drugs that inhibit platelets from aggregating to form a plug.
Sometimes curable by bone marrow transplant, but potentially fatal, aplastic anemia is characterized by decreased production of red and white blood cells and platelets (disc-shaped cells that are a key component of blood coagulation).
The CBC shows the numbers of white blood cells, red blood cells, and platelets in the blood.
The white blood cells and platelets are most likely to be affected by chemotherapy.
Low levels of platelets can cause a patient to bleed easily from a cut or other wound.
Platelets are blood cells that make the blood clot.
When patients do not have enough platelets, they may bleed or bruise easily, even from small injuries.
Patients with low blood platelets should take precautions to avoid injuries.
Medicines such as aspirin and other pain relievers can affect platelets and slow down the clotting process.
Platelets, tiny colorless cells in the blood, initiate contraction of damaged blood vessels so that less blood is lost.
Thrombocytopenia, the most common cause of coagulation disorder, is characterized by reduced numbers of circulating platelets in the blood.
Disseminated intravascular coagulation (DIC) occurs when the malfunction of clotting factors causes platelets to form clots in small blood vessels throughout the body.
This action leads to depletion of clotting factors and platelets, which are then not available at a site of injury where clotting is needed.
What the underlying causes of DIC have in common is a dysfunction that involves proteins, platelets, or other clotting factors and processes.
It represents a defective or decreased production of platelets.
Common underlying disorders include leukemia, drug toxicity, or aplastic anemia, all of which lead to decreased or defective production of platelets in the bone marrow.
Other diseases may destroy platelets outside the marrow.
The idiopathic form most commonly occurs in children and is most likely the result of production of antibodies that cause destruction of platelets in the spleen and to a lesser extent the liver.
Diagnosis usually requires a number of laboratory tests that measure concentrations of platelets and fibrinogen in the blood along with measuring prothrombin time.
Other supportive data include measuring levels of factors V and VIII, fibrinogen, hemoglobin, and platelets, any of which may be diminished or entirely depleted.
If the patient is not already bleeding, this supportive treatment may correct DIC. However, if bleeding is already occurring, a combination of transfused blood, platelets, fresh frozen plasma, or other blood products may be needed.
Some infants are placed on a ventilator to help them breathe, and some receive transfusions of platelets, which help the blood clot when there is internal bleeding.
Serum-The fluid part of the blood that remains after blood cells, platelets, and fibrogen have been removed.
When blood vessels are injured in a way that causes bleeding, platelets collect over the injured area, forming a temporary plug to prevent further bleeding.
Toxins may be absorbed into the blood stream where they destroy red blood cells and platelets, tiny cells important in blood clotting.
Infants born prematurely who become CMV infected during birth have a greater chance of complications, including pneumonia, hepatitis, decreased blood platelets.
Some of the white cells are removed, and the rest of the blood (red cells, plasma, and platelets) is returned to the body through a needle placed in the other arm.
The activity of an enzyme (glutathione peroxidase) in platelets (small blood cells essential in blood clotting) may be evaluated to assess selenium status.
The platelets stimulate the release other chemicals, called factors, which help form a strong permanent clot. vWF binds to and stabilizes factor VIII, one of the factors involved in forming the permanent clot.
Multimer analysis evaluates the structure of the vWF, and RIPA measures how much ristocetin is required to cause the clumping of platelets in a blood sample.
Wiskott-Aldrich syndrome (WAS) is a rare inherited disorder marked by a low level of blood platelets, eczema, recurrent infections, and a high risk of leukemia or lymph node tumors.
The same protein also functions in the cells that help prevent bleeding (platelets).
A less severe form of the disease, X-linked thrombocytopenia, affects mainly the platelets.
In WAS, the platelets are often too few (called thrombocytopenia) and too small.
The emphasis on erythroblast production is at the cost of producing other types of blood cells, such as platelets and other factors important for blood clotting.
One of fish oil's benefits for cardiovascular health is that it prevents blood platelets from sticking together.
When platelets stick together, they can form clumps or clots, which may lead to heart attacks or strokes.
Fish oil makes the platelets slip against each other so they can't adhere or clump.
Red blood cells carry oxygen, platelets promote blood clotting, plasma makes up the majority of your blood's volume and contains water, proteins and salts.
Explain how blood clots by platelets producing thrombin, which converts soluble fibrinogen into insoluble fibrin.
The vegetation that characterizes IE is composed of a mixture of fibrin and platelets, containing a large inoculum of bacteria.
For patients with bone marrow failure, it has been accepted practice to transfuse platelets where levels are very low.