Platelets sentence example
platelets
- It works by preventing the formation of a chemical called cyclic amp in blood platelets.
- Now, 40% of adult therapeutic doses (ATD) of platelets collected by the NBS are collected by apheresis.
- Platelets from men and women with diabetes are often hypersensitive in vitro to platelet aggregating agents.
- Platelets, apheresis means a concentrated suspension of blood platelets obtained by apheresis.
- What more could the NBS do to reduce the risk of bacterial contamination of platelets?Advertisement
- Donors might be especially called to a clinic to provide HLA class I matched platelets for a certain patient.
- Images include basophils, monocytes, eosinophils neutrophils, lymphocytes, and platelets.
- However, at presentation with relapse, she had received 2 units of red cells and 2 units of platelets which were not irradiated.
- Occasionally, if an appropriate product is not available, it may be necessary to use RhD positive platelets.
- The recipient (58 year old male) suffered fatal septic shock after transfusion with a 2-day old unit of pooled platelets.Advertisement
- In patients dependent on platelet transfusion, HPA antibodies may be a cause of refractoriness to random donor platelets.
- Alternatively selection of compatible platelets by crossmatching can be considered.
- Rhesus D negative women of childbearing age should receive Rhesus D negative platelets.
- The patient with AML was receiving multiple transfusions of both red cells and platelets, and thus presented as a case of platelet refractoriness.
- However, my blood platelets were not rising, nor were my liver enzymes decreasing.Advertisement
- In some patients with HLA antibodies, HPA antibodies may also be present requiring donor platelets matched for both type of antibodies.
- Both Rams head and Spiral wedging involve the folding of the clay on itself too build up an ever tightening spiral of clay platelets.
- Aspirin is sometimes used in children with heart conditions as it reduces the stickiness of the platelets in the blood.
- Thrombin activation of the platelets was successful only when the concentration of the platelets was high enough.
- They inhibit blood clotting by blocking thromboxane formation in blood platelets.Advertisement
- The remaining platelets are then transfused back into the patient.
- The first few days ' blood tests showed high platelets, due to the many transfusions of platelets received during surgery.
- Platelets are activated when an injury causes a blood vessel to break.
- It is this aggregation of platelets which triggers the cascade of reactions leading to blood clot formation (thrombosis).
- This recent microbiological research study gives new insight to the intracellular control mechanisms of platelets.Advertisement
- Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder caused by an abnormally low level of blood platelets, small disc-shaped cells essential to blood clotting (coagulation).
- Coagulation, or clotting, is a complex process in which specific proteins found in blood plasma combine with other blood components, including platelets, to form clots and prevent blood loss.
- Platelets are tiny colorless disc-shaped cells in the blood that collect (aggregate) in blood vessels to form a plug when a vessel is injured.
- A deficiency in platelets or a disorder that affects platelet production can disrupt clotting and severely complicate blood loss from accidental injury, surgery, and specific diseases or conditions in which bleeding can occur.
- In adults, ITP is considered an autoimmune disorder, which means that the body produces antibodies that damage some of its own products-in this case, blood platelets.Advertisement
- In addition to physically plugging breaks in blood vessel walls, platelets also release chemicals that promote clotting.
- Thrombocytopenia-A persistent decrease in the number of blood platelets usually associated with hemorrhaging.
- This may include transfusions of platelets, intravenous immunoglobulins, or prednisone.
- Prednisone is a steroid medication that decreases the effects of antibodies on platelets and eventually lowers antibody production.
- Bone marrow-The spongy tissue inside the large bones in the body that is responsible for making the red blood cells, most white blood cells, and platelets.Advertisement
- Blood is made up of red blood cells (RBCs), which carry oxygen and other materials to all tissues of the body; white blood cells (WBCs), which fight infection; and platelets, which play a part in the clotting of the blood.
- These stem cells mature through stages into RBCs, WBCs, or platelets.
- This uncontrolled proliferation of the immature cells in the bone marrow affects the production of the normal red blood cells and platelets as well.
- Low level of platelets (tiny cellular elements in blood that are an important part of coagulation).
- Plasma-A watery fluid containing proteins, salts, and other substances that carries red blood cells, white blood cells, and platelets throughout the body.Advertisement
- Whole blood-Blood which contains red blood cells, white blood cells, and platelets in plasma.
- A platelet count is a diagnostic test that determines the number of platelets in the patient's blood.
- Platelets, which are also called thrombocytes, are small disk-shaped blood cells produced in the bone marrow and involved in the process of blood clotting.
- There are normally between 150,000-450,000 platelets in each micro-liter of blood.
- Low platelet counts or abnormally shaped platelets are associated with bleeding disorders.Advertisement
- This increase is caused by a change in the shape of the platelets after removal from the body.
- This period is the best time to count the sample when using electronic instruments, because the platelets will be within a standard size range.
- Platelets can be observed in a direct blood smear for approximate quantity and shape.
- Accurate assessment of the number of platelets requires other methods of counting.
- For a proper count, the platelets should be evenly distributed in the hemacytometer.Advertisement
- For these instruments to work properly, the sample must not contain other material that might mistakenly be counted as platelets.
- Clumps of platelets will also not be counted.
- In addition, if the patient has a high white blood cell count, electronic counting may yield an unusually low platelet count because white blood cells may filter out some of the platelets before the sample is counted.
- On the other hand, if the red blood cells in the sample have burst, their fragments will be falsely counted as platelets.
- Hemocytometer-An instrument used to count platelets or other blood cells.
- It occurs in polycythemia vera and other disorders in which the bone marrow produces too many platelets.
- The normal range for a platelet count is 150,000-450,000 platelets per microliter of blood.
- An abnormally low platelet level (thrombocytopenia) is a condition that may result from increased destruction of platelets, decreased production, or increased usage of platelets.
- In idiopathic thrombocytopenic purpura (ITP), platelets are destroyed at abnormally high rates.
- Hypersplenism is characterized by the collection (sequestration) of platelets in the spleen.
- Leukemia and aplastic anemia can result in a low platelet count because of decreased production of platelets in the bone marrow.
- Abnormally high platelet levels (thrombocytosis) may indicate either a benign reaction to an infection, surgery, or certain medications; or a disease like polycythemia vera, in which the bone marrow produces too many platelets too quickly.
- Serotonin-A widely distributed neurotransmitter that is found in blood platelets, the lining of the digestive tract, and the brain, and that works in combination with norepinephrine.
- The infection may also cause significant destruction of the body's red blood cells or platelets.
- These include anemia, or breakdown of red blood cells; reduced platelets; reduced white cells; and bone marrow failure.
- Anticoagulant drugs inhibit clot formation by blocking the action of clotting factors or platelets.
- Antiplatelet drug-Drugs that inhibit platelets from aggregating to form a plug.
- Sometimes curable by bone marrow transplant, but potentially fatal, aplastic anemia is characterized by decreased production of red and white blood cells and platelets (disc-shaped cells that are a key component of blood coagulation).
- The CBC shows the numbers of white blood cells, red blood cells, and platelets in the blood.
- The white blood cells and platelets are most likely to be affected by chemotherapy.
- Low levels of platelets can cause a patient to bleed easily from a cut or other wound.
- Platelets are blood cells that make the blood clot.
- When patients do not have enough platelets, they may bleed or bruise easily, even from small injuries.
- Patients with low blood platelets should take precautions to avoid injuries.
- Medicines such as aspirin and other pain relievers can affect platelets and slow down the clotting process.
- Platelets, tiny colorless cells in the blood, initiate contraction of damaged blood vessels so that less blood is lost.
- Thrombocytopenia, the most common cause of coagulation disorder, is characterized by reduced numbers of circulating platelets in the blood.
- Disseminated intravascular coagulation (DIC) occurs when the malfunction of clotting factors causes platelets to form clots in small blood vessels throughout the body.
- This action leads to depletion of clotting factors and platelets, which are then not available at a site of injury where clotting is needed.
- What the underlying causes of DIC have in common is a dysfunction that involves proteins, platelets, or other clotting factors and processes.
- It represents a defective or decreased production of platelets.
- Common underlying disorders include leukemia, drug toxicity, or aplastic anemia, all of which lead to decreased or defective production of platelets in the bone marrow.
- Other diseases may destroy platelets outside the marrow.
- The idiopathic form most commonly occurs in children and is most likely the result of production of antibodies that cause destruction of platelets in the spleen and to a lesser extent the liver.
- Diagnosis usually requires a number of laboratory tests that measure concentrations of platelets and fibrinogen in the blood along with measuring prothrombin time.
- Other supportive data include measuring levels of factors V and VIII, fibrinogen, hemoglobin, and platelets, any of which may be diminished or entirely depleted.
- If the patient is not already bleeding, this supportive treatment may correct DIC. However, if bleeding is already occurring, a combination of transfused blood, platelets, fresh frozen plasma, or other blood products may be needed.
- Some infants are placed on a ventilator to help them breathe, and some receive transfusions of platelets, which help the blood clot when there is internal bleeding.
- Serum-The fluid part of the blood that remains after blood cells, platelets, and fibrogen have been removed.
- When blood vessels are injured in a way that causes bleeding, platelets collect over the injured area, forming a temporary plug to prevent further bleeding.
- Toxins may be absorbed into the blood stream where they destroy red blood cells and platelets, tiny cells important in blood clotting.
- Infants born prematurely who become CMV infected during birth have a greater chance of complications, including pneumonia, hepatitis, decreased blood platelets.
- Some of the white cells are removed, and the rest of the blood (red cells, plasma, and platelets) is returned to the body through a needle placed in the other arm.
- The activity of an enzyme (glutathione peroxidase) in platelets (small blood cells essential in blood clotting) may be evaluated to assess selenium status.
- The platelets stimulate the release other chemicals, called factors, which help form a strong permanent clot. vWF binds to and stabilizes factor VIII, one of the factors involved in forming the permanent clot.
- Multimer analysis evaluates the structure of the vWF, and RIPA measures how much ristocetin is required to cause the clumping of platelets in a blood sample.
- Wiskott-Aldrich syndrome (WAS) is a rare inherited disorder marked by a low level of blood platelets, eczema, recurrent infections, and a high risk of leukemia or lymph node tumors.
- The same protein also functions in the cells that help prevent bleeding (platelets).
- A less severe form of the disease, X-linked thrombocytopenia, affects mainly the platelets.
- In WAS, the platelets are often too few (called thrombocytopenia) and too small.
- The emphasis on erythroblast production is at the cost of producing other types of blood cells, such as platelets and other factors important for blood clotting.
- One of fish oil's benefits for cardiovascular health is that it prevents blood platelets from sticking together.
- When platelets stick together, they can form clumps or clots, which may lead to heart attacks or strokes.
- Fish oil makes the platelets slip against each other so they can't adhere or clump.
- Red blood cells carry oxygen, platelets promote blood clotting, plasma makes up the majority of your blood's volume and contains water, proteins and salts.
- Explain how blood clots by platelets producing thrombin, which converts soluble fibrinogen into insoluble fibrin.
- The vegetation that characterizes IE is composed of a mixture of fibrin and platelets, containing a large inoculum of bacteria.
- For patients with bone marrow failure, it has been accepted practice to transfuse platelets where levels are very low.