Platelet sentence example

platelet
  • Defects in platelet adhesion may also be related to excessive nitric oxide (NO) production.
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  • If a platelet and another blood cell pass through the counter at the same time, the instrument will not count the larger cell, which will cause the instrument to accidentally miss the platelet.
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  • Next, blood coagulation rapidly replaces this unstable platelet plug with a stable fibrin clot.
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  • The low platelet count may be discovered in the course of a routine blood test.
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  • Platelet transfusion through negatively charged filters can also activate the contact system and give rise to significant hypotension in patients receiving ACE inhibitors.
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  • Propofol inhibits platelet aggregation which could reduce the risk of thrombosis.
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  • Just to confuse things further, there is now an acceptance that in some people aspirin may not prevent platelet aggregation.
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  • Diagnostic features are a normal platelet count with a prolonged bleeding time.
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  • Age was the only significant factor by multivariate analyzes, with older patients having lower platelet counts at 1 year posttreatment.
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  • Haemostatic mechanisms control blood flow by regulating platelet adherence and fibrin deposition and various haemostatic proteins have been shown to regulate angiogenesis.
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  • As NSAIDs can interfere with platelet function, they should be used with caution in patients with intracranial hemorrhage and bleeding diathesis.
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  • Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty.
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  • Platelets from men and women with diabetes are often hypersensitive in vitro to platelet aggregating agents.
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  • All received intravenous immunoglobulin, and four received platelet concentrate.
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  • Additional HPA typing can be performed on request, please discuss with the platelet immunology laboratory.
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  • Clinical deficiency may increase platelet aggregation and reduce the life span of red blood cells.
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  • The mean platelet count nadir measured was approximately 40% of baseline.
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  • In patients dependent on platelet transfusion, HPA antibodies may be a cause of refractoriness to random donor platelets.
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  • The patient with AML was receiving multiple transfusions of both red cells and platelets, and thus presented as a case of platelet refractoriness.
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  • This problem has been particularly apparent in small children receiving apheresis platelet concentrates, which contain large volumes of plasma from single donors.
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  • These drugs are sometimes used to treat patients with a low platelet count due to idiopathic thrombocytopenic purpura (ITP ).
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  • However, in the condition known as thrombotic thrombocytopenia purpura the use of platelet concentrates is in fact particularly hazardous.
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  • Furthermore, a number of patients never develop HLA antibodies nor do they become refractory, despite receiving multiple platelet transfusions.
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  • Before performing fetal sampling and requesting these investigations, please contact the platelet immunology laboratory.
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  • Garlic is also able to inhibit platelet stickiness, reducing the risk of blood clots.
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  • Like the adult form, platelet transfusions should NOT be given.
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  • It is not feasible to conduct large, highly expensive multicentre trials of every modification to platelet storage.
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  • These drugs are sometimes used to treat patients with a low platelet count due to idiopathic thrombocytopenic purpura (ITP).
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  • The platelet phase is central to thrombus formation inside blood vessels.
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  • Activation results in platelet adhesion, aggregation and degranulation leading to thrombus growth.
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  • Platelet thrombus formation and aggregation are reduced, and fibrinolytic capacity increased, in patients treated with statins.
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  • A child may also develop extra vascular tissue with a deeper hemangioma which could cause platelet problems or anemia.
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  • Animals that have feline distemper have low platelet and hematocrit counts.
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  • Taking a regular supplement of cayenne can reduce cholesterol, triglyceride levels, and platelet aggregation.
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  • This syndrome is associated with abnormal blood clotting, low blood platelet counts, and migraine headaches.
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  • The platelet plug then binds coagulation proteins to form a clot that stops bleeding.
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  • Diagnostic tests will begin with a complete blood count (CBC), including a platelet count.
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  • Platelet aggregation tests may be performed to evaluate platelet function, particularly if the platelet count is low.
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  • Platelet transfusions are not recommended for routine treatment of ITP.
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  • If platelet levels do not improve within one to four months, or high doses of prednisone are required, splenectomy may be recommended.
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  • A platelet count is a diagnostic test that determines the number of platelets in the patient's blood.
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  • Low platelet counts or abnormally shaped platelets are associated with bleeding disorders.
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  • High platelet counts or low platelet counts sometimes indicate disorders of the bone marrow.
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  • Patients who have leukemia, polycythemia vera, or aplastic anemia are given periodic platelet count tests to monitor their health.
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  • Platelet counts use a freshly collected blood specimen to which a chemical called EDTA has been added to prevent clotting before the test begins.
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  • After collection, the mean platelet volume of EDTA-blood will increase over time.
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  • Errors in platelet counting are more common when blood is collected from capillaries than from veins.
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  • Electronic counting instruments sometimes produce artificially low platelet counts.
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  • Because platelet counts are sometimes ordered to diagnose or monitor bleeding disorders, patients with these disorders should be cautioned to watch the puncture site for signs of additional bleeding.
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  • Risks for a platelet count test are minimal in normal individuals.
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  • The normal range for a platelet count is 150,000-450,000 platelets per microliter of blood.
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  • An abnormally low platelet level (thrombocytopenia) is a condition that may result from increased destruction of platelets, decreased production, or increased usage of platelets.
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  • Another cause of a low platelet count is an enlarged spleen.
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  • Leukemia and aplastic anemia can result in a low platelet count because of decreased production of platelets in the bone marrow.
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  • All of these diseases produce reduced platelet counts.
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  • These tests mostly involve blood analysis in the form of a white blood cell count, complete blood count, platelet count, and serum calcium evaluation.
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  • Aspirin and products containing aspirin should be avoided, as they can affect platelet counts.
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  • Von Willebrand's disease, a hereditary disorder with prolonged bleeding time, is due to a clotting factor deficiency and impaired platelet function.
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  • Tests for thrombocytopenia include coagulation tests that may reveal a decreased platelet count and prolonged bleeding time.
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  • If these tests indicate that platelet destruction is causing the disorder, the physician may order a bone marrow biopsy.
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  • Von Willebrand's disease is diagnosed by ordering laboratory tests that reveal a prolonged bleeding time, absent or reduced levels of factor VIII, and a normal platelet count.
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  • Sometimes, corticosteroids or immune globulin may be given to improve platelet production.
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  • Blood tests show a high white blood cell count, high platelet count, a high level of protein in the blood serum, and mild anemia.
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  • A deficiency or abnormality in vWF can interfere with the formation of the temporary platelet plug and affect the normal survival of factor VIII.
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  • Patients with type 2B VWD should not be treated with this medication, since DDAVP can induce dangerous platelet clumping.
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  • If bleeding becomes a problem, the patient may require frequent blood or platelet transfusions or operations to control the bleeding.
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  • Infection results when excess bone impairs the immune system, and hemorrhage can occur when platelet production is disrupted.
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  • The blood of Wiskott-Aldrich patients shows a low platelet count and a weak immune (antibody) response.
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  • Seizures occur in roughly 1 of every 3,000 children, and about 1 in every 30,000 experience low platelet counts after having the shot.
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  • A deficiency in platelets or a disorder that affects platelet production can disrupt clotting and severely complicate blood loss from accidental injury, surgery, and specific diseases or conditions in which bleeding can occur.
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  • The primary functions of a platelet count are to assist in the diagnosis of bleeding disorders and to monitor patients who are being treated for any disease involving bone marrow failure.
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  • In addition, if the patient has a high white blood cell count, electronic counting may yield an unusually low platelet count because white blood cells may filter out some of the platelets before the sample is counted.
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  • Abnormally high platelet levels (thrombocytosis) may indicate either a benign reaction to an infection, surgery, or certain medications; or a disease like polycythemia vera, in which the bone marrow produces too many platelets too quickly.
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  • Rarely, inflammations of the heart or kidneys, a drop in platelet count (causing episodes of difficult-to-control bleeding), or reactivation of an old tuberculosis infection can occur.
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  • Once a person is diagnosed with VWD, further testing such as vWF multimer analysis and ristocetin-induced platelet aggregation (RIPA) should be performed to determine the subtype.
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  • It can also lead to HELLP syndrome, with hemolysis (destruction) of red blood cells, elevated liver enzymes signaling liver damage, and low platelet count (leading to bleeding problems).
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  • If the factor VIII concentrates are unable to manage a severe bleeding episode, then blood products called cryoprecipitates, which contain concentrated amounts of vWF, or platelet concentrates should be considered.
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