Two gauze pads, one soaked in salt water or bicarbonate and the other in pilocarpine, a drug that stimulates sweating, are placed under the electrodes.
A tiny electric current is applied to the skin for five to ten minutes to carry the pilocarpine into the skin.
A very small electrical current is then applied to the area, which drives the pilocarpine into the skin.
A dry piece of filter paper is taped to the area where the pilocarpine was applied.
In this test, a small amount of the drug pilocarpine is placed on the skin.
PILOCARPINE, C11H16N202, an alkaloid found, together with isopilocarpine and other related compounds, in the leaves of jaborandi (Pilocarpus pennatifolius).
Jowett is of the opinion that pilocarpine and isopilocarpine are stereo-isomers of the structure: - 7CH N.
(1) Pyridine group. Piperine; conine; trigonelline; arecaidine; guvacine; pilocarpine; cytisine; nicotine; sparteine.
Do not employ such physiological antagonists as pilocarpine or morphine, for the lethal actions of all these drugs exhibit not mutual antagonism but coincidence.
Pilocarpine has an action closely allied to that of nicotine, but as it is much less poisonous (the effects produced by small doses being chiefly excessive sweating and salivation), it is capable of being utilized in medicine.