Phagocytes Sentence Examples
Phagocytes act as scavengers in ridding the body of noxious particles, and more especially of harmful bacteria.
The vanguard of this advancing army is composed of a more or less compact layer of the mono-nuclear phagocytes (polyblasts) accompanied by numerous new vessels.
This is accomplished by a twofold agency, for while numbers of them are seized upon by the granulation phagocytes, others are broken up and dissolved by the liquid filling the granulation interspaces (Afanassieff).
They also appear to have in certain cases a paralysing action on the cells which act as phagocytes.
Then as regards natural powers of destroying bacteria, phagocytosis aided by chemiotaxis plays a part, and it can be understood that an animal whose phagocytes are attracted by a particular bacterium will have an advantage over one in which this action is absent.Advertisement
He also showed that the development of artificial immunity is attended by the appearance of phagocytosis; also, when an anti-serum is injected into an animal, the phagocytes which formerly were indifferent might move towards and destroy the bacteria.
Cold, by some means or other, causes the pigment-bodies to shift from the normal positions, and to transfer themselves to other layers of the hair, where they are attacked and devoured by phagocytes.
Under the influence of exposure to intense cold a small mammal has been observed to turn white in a single night, just as the human hair has been known to blanch suddenly under the influence of intense emotion, and in both cases extreme activity of the phagocytes is apparently the inducing cause.
Foreign cells are also swallowed by cells called phagocytes.
Regulated expression and release of the IL-1 decoy receptor in human mononuclear phagocytes.Advertisement
Closely on the advance of this .army of phagocytes or scavenger cells follows the third line of defenders, the connective tissue cells or fibroblasts.
In a period varying from twenty-four to thirty hours there is marked evidence of the removal of the degenerated cellular elements in the damaged zone by the mono-nuclear phagocytes.
Given a noxious agent in a tissue, such, let us say, as a localized deposit of certain bacteria, the phagocytes swarm towards the locality where the bacteria have taken up their residence.
The phagocytes are attracted from the blood vessels and elsewhere towards the noxious focus by the chemiotaxis exerted upon them by the toxins secreted by the bacteria contained within it.
The chemiotaxis in this instance is positive, but the toxins from certain other bacteria may act negatively; and such bacteria are fraught with particular danger from the fact that they can spread through the body unopposed by the phagocytes, which may be looked upon as their natural enemies.Advertisement
Though this may dishearten the systematist, Scourfield (1900) reminds us that " It was in a water-flea that Metschni koff first saw the leucocytes (or phagocytes) trying to get rid of disease germs by swallowing them, and was so led to his epochmaking discovery of the part played by these minute amoeboid corpuscles in the animal body."
However if infection disseminates in the blood, the widespread activation of phagocytes in the bloodstream initiates the sepsis response.
The innate immune system is made up of the skin (which acts as a barrier to prevent organisms from entering the body); white blood cells called phagocytes; a system of proteins called the complement system; and chemicals called interferons.
When phagocytes encounter an invading organism, they surround and engulf it in order to destroy it.
This allows the phagocytes to begin engulfing and destroying the organism.Advertisement
Disorders of innate immunity affect phagocytes or the complement system.
Blood contains antibodies, lymphocytes, phagocytes, and complement components, all of the major immune components that might cause immunodeficiency.
It has, however, since been found that in other kinds of insects the tissues degenerate and break down without the intervention of phagocytes.
This reaction is carried out by the mobile phagocytes sometimes alone, sometimes with the aid of the vascular phagocytes, or of the nervous system."
Ingestion and dissolution of the Trypanosomes by phagocytes has frequently been observed; and it is probable also that the haematopoietic organs secrete some substance which exerts a harmful action on the parasites, and causes them to undergo involution and assume weird-looking " amoeboid " and " plasmodial " forms.Advertisement
We have no distinct proof that there occurs in active immunity any education of the phagocytes, in Metchnikoff's sense, that is, any increase of the inherent ingestive or digestive activity of these cells.