It is thought that PML is linked to opportunistic infection with the JC virus (a human polyomavirus ).
Opportunistic-Infection caused by microorganisms that are usually harmless, but which can cause disease when a host's resistance is lowered.
The child loses weight, becomes very weak, and if untreated eventually dies from an opportunistic infection.
The most common opportunistic infection in children with XHIM is a lung disease known as Pneumocystis carinii pneumonia (PCP).
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