Niacin, also known as nicotinic acid or vitamin B3, has been shown to reduce LDL levels by 10 to 20 percent and raise HDL levels by 15 to 35 percent.
"The Importance of Nicotinic Acetylcholine Receptors in Schizophrenia, Bipolar Disorder, and Tourette's Syndrome."
Niacin, an essential nutrient, is often referred to as vitamin B3 or nicotinic acid.
On oxidation with chromic or nitric acids, or potassium permanganate, it yields nicotinic acid or (3-pyridine carboxylic acid, C 5 H 4 N CO 2 H; alkaline potassium ferricyanide gives nicotyrine, C10H10N2, and hydrogen peroxide oxynicotine, C10H14N20.
Chemically it is methyl-tetrahydro-nicotinic acid.
Trigonelline, C7H7N02, the methyl betaine of nicotinic acid, was discovered in 1885 by E.
With baryta it yields methylamine, and when heated with concentrated hydrochloric acid to 260° C. it yields methyl chloride and nicotinic acid.