Diagnosis is more easily accomplished in cases in which non-specific symptoms appear in combination with symptoms more specific to porphyria, like neuropathy, sensitivity to sunlight, or certain other manifestations.
A poorly fitting shoe can rub against a toe, bringing on an infection, but due to peripheral neuropathy and weak circulation, the patient neither feels nor fights the infection.
It is also known as hereditary motor and sensory neuropathy and is sometimes called peroneal muscular atrophy, referring to the muscles in the leg that are often affected.
Creange. "Neurophysiological testing correlates with clinical examination according to fiber type involvement and severity in sensory neuropathy."
These issues often stem from neuropathy and poor circulation, and can result in a number of symptoms, ranging from loss of sensation to swelling.
The pain associated with cancer, persistent and degenerative conditions, and neuropathy, or nerve damage, is included in the chronic category.
It is also a powerful antioxidant which helps to prevent free radical damage which could lead to cancer, neuropathy and heart disease.
Diabetic shoes are frequently required because excess glucose can cause a condition called peripheral neuropathy in the feet.
According to The University of Chicago's Jack Miller Center for Peripheral Neuropathy, celiac disease has also been shown to cause ataxia, a condition marked by jerky uncoordinated muscle movements.
There has been some success with managing the pain from diabetic neuropathy; however it is less effective with neuropathy stemming from auto-immune diseases.