How to use Myopathies in a sentence

myopathies
  • Disorders in which skeletal muscle is the primary target of the mitochondrial dysfunction are called mitochondrial myopathies.

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  • Dermatomyositis is one of a group of relatively uncommon diseases known as inflammatory myopathies, or inflammatory disorders of the muscles.

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  • Myopathies are diseases of skeletal muscle that are not caused by nerve disorders.

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  • There are many different types of myopathies.

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  • Most myopathies are degenerative, meaning they become more pronounced over time.

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  • There is great variety among myopathies, but what they all share are effects on the skeletal muscles.

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  • The main causes of myopathies are genetic, inflammatory (caused by infection), endocrine (hormonal), and metabolic (errors in how cells function).

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  • With each of the inherited myopathies, a genetic defect is linked to a lack of, or defect in, one of the proteins needed for normal muscle cell function.

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  • Most, but not all, of these genetic myopathies are inherited through an autosomal dominant pattern of inheritance.

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  • Mitochondrial myopathies are inherited only through the mother, since sperm do not contain mitochondria.

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  • In some cases, myopathies can be caused by a malfunctioning endocrine gland that produces either too much or too little of the chemical messengers called hormones.

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  • Some myopathies are caused by inflammation.

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  • While considered a separate group of diseases, the muscular dystrophies also involve muscle wasting and can be described as myopathies.

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  • About 14 percent of myopathies are inherited.

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  • Worldwide the rate of inflammatory myopathies is about five to ten individuals per 100,000.

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  • These myopathies are more often seen in women.

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  • The rate of metabolic and endocrine myopathies was, as of 2004, not known.

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  • Diagnostic tests can help differentiate among the different types of myopathies, as well as between myopathy and other neuromuscular disorders.

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  • Genetic tests are available for a few myopathies.

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  • As of 2004, there was no cure for many myopathies.

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  • Muscular dystrophy is generally a more serious disease than many other types of myopathies.

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  • As of 2004 there is no way to prevent the genetic mutations that cause myopathies, nor are there ways to prevent metabolic and endocrine failures that result in myopathies.

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  • Inflammatory myopathies often occur as a result of exposure to viruses or drugs, but it is almost impossible to predict their development.

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  • Individuals with known myopathies who wish to become parents may want to seek genetic counseling before attempting to have children.

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