The complex fat of the myelin becomes altered chemically, while the other components of the sheath break down.
In secondary encephalitis, symptoms usually begin five to ten days after the onset of the disease itself and are related to the breakdown of the myelin sheath that covers nerve fibers.
A little later the breaking down of the whole axon, both axis cylinder and myelin sheath alike, seems to occur simultaneously throughout its entire length distal to the place of severance.
Some other glycerides isolated from natural sources are analogous in composition to tristearin, but with this difference, that the three radicals which replace hydrogen in glycerin are not all identical; thus kephalin, myelin and lecithin are glycerides in which two hydrogens are replaced by fatty acid radicals, and the third by a complex phosphoric acid derivative.
The Schwann cell has an extensive cytoplasm which allows it to wrap a myelin sheath around nerve axons.
This is due to the fact that the fibers in the spinal cord and cerebral cortex have not been completely covered in myelin, the protein and lipid sheath that aids in processing neural signals.
Myelin also contains about 20% of proteins whose prime role is to mediate adhesion between adjacent Schwann cells.
These sclerotic plaques are the decay in the myelin sheathing of the myelinated axons from distinct regions within the CNS.
generalizes to include the mouse's own myelin.
Most of our work centers on one called myelin associated glycoprotein, or MAG.
insulate are surrounded by an insulating fatty sheath comprised of a complex protein called myelin.
At the site of a lesion, a nerve insulating material, called myelin, is lost.
This causes the body's immune system to attack the myelin covering on nerves.
A gene in mice, similar to a human gene, has been shown to be important in making myelin.
The Cycle of Damage and Recovery Once the inflammation within the CNS subsides, cells within the CNS begin to repair the damaged myelin.
Schwann cell - produces myelin in the peripheral nervous system.
Often many axons remain intact but are rendered useless by loss of their insulating myelin.
One of the features of myelination is that it leaves distinct gaps in the myelin layer where the axon is not surrounded by myelin.
In MS, the body's immune system attacks myelin as if it were an invading bacteria or virus.
myelin sheath a layer of fatty protein that protects the nerves.
myelin proteins, three received moderate doses, and three received nothing.
myelin repair and multiple sclerosis Why me?
myelin damage in MS Why are stem cells important?
myelin in the brain and spinal cord.
This was causing pressure on the nerve root causing loss of myelin sheath.
Less commonly the problem lies in the insulating myelin sheath.
In MS, damage or scarring occurs to the myelin sheath a layer of fatty protein that protects the nerves.
synthesized as a precursor for cholesterol, myelin, and steroid hormones.
Fruit and vegetables are a vital source of antioxidant vitamins, which are important in helping to maintain and protect myelin.
Squalene is a naturally occurring molecule absorbed from food, and synthesized as a precursor for cholesterol, myelin, and steroid hormones.
A nerve can be likened to an electrical wire, in which the wire part is the axon of the nerve and the insulation surrounding it is the myelin sheath.
The job of the myelin is to help messages travel very fast through the nerves.
Children who have problems with the myelin have CMT type 1 and children who have abnormalities of the axon have CMT type 2.
The most common type of CMT, called CMT1A, is caused by a mutation in a gene called peripheral myelin protein 22 (PMP22) located on chromosome 17.
The job of this gene is to make a protein (PMP22) that makes up part of the myelin.
Another type of CMT, called CMT1B, is caused by a mutation in a gene called myelin protein zero (MPZ), located on chromosome 1.
The job of this gene is to make the layers of myelin stick together as they are wrapped around the axon.
Another type of CMT, called CMTX, is usually considered a subtype of CMT1 because it affects the myelin, but it has a different type of inheritance than type 1 or type 2.
The job of this gene is to code for a class of protein called connexins that form tunnels between the layers of myelin.
This is because their normal copy of the Cx32 gene does make normal myelin.
Demyelination-Disruption or destruction of the myelin sheath, leaving a bare nerve.
The syndrome is due to inflammation and loss of the myelin covering of the nerve fibers, often associated with an acute infection.
Multiple sclerosis-A progressive, autoimmune disease of the central nervous system characterized by damage to the myelin sheath that covers nerves.
Krabbe disease: an inherited disorder characterized by a deficiency of the enzyme galactosylcereamidase, resulting in destruction of myelin, the fatty material that surrounds and insulates many of the nerves.
The peroxisomal disorders that include effects on the growth of the myelin sheath are considered to be part of a group of genetic disorders referred to as leukodystrophies.
In X-ALD there is a deficiency in the enzyme that breaks down VLCFAs, which then accumulate in myelin and the adrenal glands.
The Myelin Project. 2136 Gallows Rd., Suite E, Dunn Loring, VA 22027.
Many nerve cells have long, wire-like axons that are covered by an insulating layer called the myelin sheath.
In untreated PKU patients, abnormally high phenylalanine levels in the blood and brain can produce nerve cells with deformed axons and dendrites and cause imperfections in the myelin sheath referred to as hypomyelination and demylenation.
This loss of myelin can short circuit nerve impulses (messages) and interrupt cell communication.
A 2003 study found that schizophrenia and bipolar disorder could have similar genetic causes that arise from certain problems with genes associated with myelin development in the central nervous system.
In adults and children over the age of one-and-a-half years, the myelin sheath should be completely formed, and, as a result, all the toes will curl under (planter flexion reflex).
Axons are covered by sheaths of an insulating whitish substance called myelin, and the region in which they lie is accordingly called white matter.
White matter-A substance, composed primarily of myelin fibers, found in the brain and nervous system that protects nerves and allows messages to be sent to and from the brain and various parts of the body.
A University of Michigan study found that exposure to the measles virus could interfere with the proper development of myelin, a protein found in the area that protects the nerve fibers in the brain.
When myelin fails to develop properly, the nerve fibers do not work correctly and brain abnormalities such as autism symptoms may occur.
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