Mutagenesis sentence example

mutagenesis
  • Another method of genetic modification, called mutagenesis, dates to the early part of the twentieth century.
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  • Site directed mutagenesis has been used to generate such mutants.
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  • We use site-directed mutagenesis to couple this information to structural features of the proteins.
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  • Cloning, mutagenesis and expression The domains were amplified from cDNA using polymerase chain reaction (PCR ).
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  • Our present study clearly demonstrates that anticancer chemotherapy can induce mutagenesis in vivo in various pediatric cancer patients.
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  • We are using molecular genetic approaches, in particular random mutagenesis, to analyze fungal genes involved in the disease process.
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  • For this we are using molecular modeling to investigate docking of the novel compounds, as well as conventional mutagenesis and expression techniques.
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  • The mutants were generated by random transposon mutagenesis with the Tn pho A transposon.
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  • The insertion mutagenesis strategy was co-ordinated with acquisition of the DNA sequence of the PAI.
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  • Using this technique in combination with another mutagenesis method called saturation mutagenesis the ee value has been improved to more than 90 per cent.
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  • One approach is to change the natural substrate specificity of an enzyme through mutagenesis.
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  • The function of genes located by transposon mutagenesis and sequencing was tested after sub-cloning of open reading frames into broad host range shuttle vectors.
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