The therapeutic scenario has moved from dapsone monotherapy in the 1970s to MDT using drugs such as dapsone monotherapy in the 1970s to MDT using drugs such as dapsone, rifampicin and clofazimine.
There was no significant difference in their median duration of successful monotherapy.
Significant advantages for Enbrel in combination with methotrexate compared with Enbrel monotherapy and methotrexate monotherapy were also observed after 24 months.
LESCOL is efficacious in monotherapy or in combination with bile acid sequestrants.
Helvaci, M., et al. "Efficacy of hepatitis B vaccination and interferon-[alpha]-2b combination therapy versus interferon-[alpha]-2b monotherapy in children with chronic hepatitis B."
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