How to use Monoclonal in a sentence

monoclonal
  • Monoclonal antibodies are used to fight cancer cells in much the same way as antibodies that are produced by the body's own immune system work to fight infection.

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  • In order to secure CAT's human monoclonal antibody drug pipeline into the future, CAT continues to develop its pool of drug targets.

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  • One example is the 5T4 oncofoetal antigen originally defined by a monoclonal antibody raised against human trophoblast.

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  • Elan researchers have recently shown for the first time that certain monoclonal antibodies can cross the blood-brain barrier.

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  • Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty.

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  • Of interest is the Dynabeads assay, an alternative method for providing CD4 cell counts using anti-CD4 monoclonal antibody-coated magnetic beads.

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  • Clinical Outcome of Colorectal Cancer Patients treated with human monoclonal anti-idiotypic antibody.

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  • The original rat monoclonal antibodies had been prepared from ascitic fluid, crudely fractionated with ammonium sulfate.

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  • A solution to the immunogenicity of rodent monoclonal antibodies in human therapy would be to derive human antibodies directly from humans.

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  • Successful treatment of active ankylosing spondylitis with the anti-tumor necrosis factor alpha monoclonal antibody infliximab.

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  • A population of rat hybridoma cells were transfected with an expression plasmid encoding a humanized monoclonal antibody.

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  • Proprietary CAT-354 is a fully human anti-IL13 monoclonal antibody being developed by CAT, initially as a potential treatment for severe asthma.

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  • It is the first fully human monoclonal antibody for RA that works by targeting a key inflammatory protein, Tumor Necrosis Factor.

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  • Monoclonal antibodies used as a treatment may for example destroy the blood cells that are causing myositis.

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  • If clear positive results are not obtained with two monoclonal anti-D reagents it is safer to classify the patient as D negative.

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  • Therefore, in spite of the variable proportions of each component, our results confirm that the synovial sarcoma is of monoclonal origin.

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  • They include substances such as interferons, interleukins, growth factors, monoclonal antibodies, and vaccines.

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  • As of 2003, more sensitive monoclonal assays had been developed for measuring hormone levels in the blood serum of women with PCOS, thus allowing earlier and more accurate diagnosis.

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  • Immunofluorescence monoclonal antibody testing is very sensitive technique that gives a rapid diagnosis of inclusion conjunctivitis.

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  • Obviously their selection must be compatible with the maintenance of antigen binding in the final humanized monoclonal antibody.

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  • Negative controls utilized a mouse monoclonal antibody raised against a non-mammalian epitope.

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