Such doses can be achieved in patients receiving 1 gram bolus intravenous doses of methylprednisolone.
Beneficial effect of methylprednisolone sodium succinate in the treatment of acute spinal cord injury (translation of Japanese ).
Beneficial effect of methylprednisolone sodium succinate in the treatment of acute spinal cord injury (translation of Japanese).
Gluococorticoids, such as prednisone or methylprednisolone, are often given to decrease any swelling and to suppress the immune response.
Effective drug therapy for spinal cord injury was demonstrated in 1990, when methylprednisolone, the first drug shown to improve recovery from spinal cord injury, was approved for standard use.
Completely paralyzed patients given methylprednisolone recover an average of about 20 percent of their lost motor function, compared to only 8 percent recovery of function in untreated patients.
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