Kinases sentence example
Other kinases at the cytosolic surface of the plasma membrane then catalyze phosphorylation of Protein Kinase B, activating it.
Its amino acid sequence shows much greater homology to consensus sequences derived from protein serine/threonine kinases than to the consensus for protein tyrosine kinases.
The gene family encoding protein kinases is the most commonly mutated in human cancer.
These have been shown to interact with and inhibit tyrosine kinases.
We have recently identified a number of putative regulatory genes, including cyclin-dependent kinases of Toxoplasma.Advertisement
The motif is only observed in the Polo-like kinases.
Six members of the p21-activated kinase (PAK) family of protein kinases have been identified to date.
Some of these proteins belong to a group called the tyrosine kinases.
The GTPases Rac and Cdc42 promote outgrowth of neurites while Rho promotes their retraction, by switching on the kinases PAK and ROK respectively.
Similar to protein kinases also lipid kinase activity is reversed by lipid phosphatases.Advertisement
In both instances the residues of the protein kinases that are dephosphorylated are situated within the activation segment of the kinase.
Both receptor and non-receptor tyrosine kinases play pivotal roles in these signaling pathways.
Lastly, we show that signaling pathways controlled by Src-family kinases are modulated in replicon cells.
Recognition of foreign antigens at the TCR leads to tyrosine phosphorylation of the ITAM motifs of the -chain by Src family kinases.