Kinases sentence example

kinases
  • Other kinases at the cytosolic surface of the plasma membrane then catalyze phosphorylation of Protein Kinase B, activating it.
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  • Its amino acid sequence shows much greater homology to consensus sequences derived from protein serine/threonine kinases than to the consensus for protein tyrosine kinases.
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  • The gene family encoding protein kinases is the most commonly mutated in human cancer.
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  • These have been shown to interact with and inhibit tyrosine kinases.
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  • We have recently identified a number of putative regulatory genes, including cyclin-dependent kinases of Toxoplasma.
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  • The motif is only observed in the Polo-like kinases.
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  • Six members of the p21-activated kinase (PAK) family of protein kinases have been identified to date.
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  • Some of these proteins belong to a group called the tyrosine kinases.
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  • The GTPases Rac and Cdc42 promote outgrowth of neurites while Rho promotes their retraction, by switching on the kinases PAK and ROK respectively.
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  • Similar to protein kinases also lipid kinase activity is reversed by lipid phosphatases.
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  • In both instances the residues of the protein kinases that are dephosphorylated are situated within the activation segment of the kinase.
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  • Both receptor and non-receptor tyrosine kinases play pivotal roles in these signaling pathways.
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  • Lastly, we show that signaling pathways controlled by Src-family kinases are modulated in replicon cells.
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  • Recognition of foreign antigens at the TCR leads to tyrosine phosphorylation of the ITAM motifs of the -chain by Src family kinases.
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