"I'm afraid it will irritate your wound," she reasoned.
She knew that her going in during the night at an unusual hour would irritate him.
All of them injected into the blood in large doses act as muscle and nerve poisons, and during their excretion by the kidney usually irritate it severely, but only a few are absorbed in sufficient amount to produce similar effects when given by the mouth.
Agrippina's angry remonstrances served only to irritate Nero, and caresses equally failed.
He had no idea if she'd respond or not; he did it more to irritate her than because he was thirsty.
The futile and thriftless yet busy and self-important king was one of those sovereigns who irritate their subjects into opposition by injudicious activity.
Those which act upon the alimentary canal: Simple bitters such as quassia wood, columbo root, taraxacum, gentian, chiretta, and many others, irritate gently the mucous membrane of the stomach and bowels, and by increasing the secretions improve the appetite and digestion.
This singular way of electing members for the principal city in the kingdom could not fail further to irritate the parties.
Vesica, a bladder), which irritate sufficiently to cause the blood-serum to exude and form vesicles or blisters, e.g.
Most of the responsibility lay with the Vatican, which had arranged the procession in the way best calculated to irritate Italian feeling, but little excuse can be offered for the failure of the Italian authorities to maintain public order.
The idea of a Spanish marriage excited the wrath of Knox, whose interviews with Mary did nothing but irritate both parties and alienate the politicians from the more enthusiastic Protestants.
Essex, though bitterly mortified, at once threw all his energies into the endeavour to procure for Bacon the solicitorship; but in this case also, his method of dealing, which was wholly opposed to Bacon's advice,' seemed to irritate the queen.
All that could be said was, that it was expedient in a widespread empire that the power of final decision should be lodged somewhere, and that it was also expedient not to use that power in such a way as to irritate those whom it was the truest wisdom to conciliate.
"It was a small estate that brought in no profit," replied Prince Andrew, trying to extenuate his action so as not to irritate the old man uselessly.
He was still watching her – probably wondering what he had done to irritate her – maybe even wondering if she was upset or merely busy.
The Jagiellos, as a rule, prudently avoided committing themselves to any political system which might irritate the still distant but much-dreaded Turk, but when their dominions extended so far southwards as to embrace Moldavia, the observance of a strict neutrality became exceedingly difficult.
Substances like pepper, cayenne pepper, mustard, horse-radish and ginger irritate the stomach and bowel much in the same way, but are more pungent, and are consequently used as condiments.
When swallowed in small doses they slightly irritate the mouth and gastric mucous membrane, increasing the secretions and producing a feeling of warmth.
During excretion they irritate the kidneys and the sweat-glands, and thereby increase the excretion of urine and of sweat.