Quinine still remains the one specific. In serious cases it should not be given in solid form, but in solution by the stomach, rectum, or - better - hypodermically (Manson).
Morphine may be given hypodermically to mitigate the pain.
The drug should regularly be given hypodermically, and it is important to note that if the injection be made immediately under the skin, an abscess, or considerable discomfort, may ensue.
They may be applied externally as fomentations, for the relief of tormina; by rectal injection for the relief of the tenesmus and irritability of the bowel; hypodermically in advanced cases, for the relief of the general distress.