Hirschsprung-s-disease sentence example
Children diagnosed with Hirschsprung's disease lack nerve cells (ganglia) in the large intestine, severely affecting the wavelike movements that propel material through the colon.
Symptoms can be removed in at least 90 percent of children born with Hirschsprung's disease.
Motility disorders such as Hirschsprung's disease and psuedo-obstruction may cause blockages by retarding peristalsis, the intestinal muscle contractions that move food and waste.
Proof that genetic factors contribute to Hirschsprung's disease is that it is known to run in families, and it has been seen in association with some chromosome abnormalities.
Molecular diagnostic techniques have identified many genes that cause susceptibility to Hirschsprung's disease.Advertisement
While two-thirds of cases are diagnosed in the first three months of life, Hirschsprung's disease may also be diagnosed later in infancy or childhood.
Most infants with Hirschsprung's disease achieve good bowel control after surgery, but a small percentage of children may have lingering problems with soilage or constipation.
Parents should understand that toilet teaching may be delayed in children who have had surgery for Hirschsprung's disease.
Children who have had surgical correction of Hirschsprung's disease are also at a higher risk for constipation and dehydration.