Globin Sentence Examples

This circumstance substantially reduces the amount of alpha globin that the body produces.

By a dilute acid haemoglobin is decomposed into globin, and " haematin," a ferri-pyrrol derivative of the probable formula C34H34N4FeOs; under certain conditions the iron-free " haematoporphyrin " is obtained.

They found that zeta globin was able to replace the faulty beta globin, in the same way that gamma globin can.

Thalassemias are classified according to the globin that is deficient.

Individuals inherit from each parent a gene controlling alpha globin production.

Two spots (called loci) on these genes control alpha globin production.

It is caused by a change in the gene for the beta globin component of hemoglobin.

These changes cause little or no globin to be produced.

There are rare exceptions, notably with beta thalassemia, where globin gene mutations exhibit a dominant pattern of inheritance in which only one gene needs to be altered in order to see disease expression.

Most individuals have four normal copies of the alpha globin gene, two copies on each chromosome 16.

Alpha globin is also a component of fetal hemoglobin.

Absence of one functioning alpha globin gene leads to a condition known as silent alpha thalassemia trait.

Alpha thalassemia trait occurs when two alpha globin genes are missing or not functioning.

This syndrome can be caused by a deletion of a significant amount of chromosome 16, affecting the alpha globin genes.

Alpha thalassemia major results from the deletion of all four alpha globin genes, such that there are no functioning alpha globin genes.

Most individuals have two normal copies of the beta globin gene, which is located on chromosome 11 and makes the beta globin component of normal adult hemoglobin.

No beta globin is produced with a beta0 mutation, and only a small fraction of the normal amount of beta globin is produced with a beta+ mutation.

When an individual has one normal beta globin gene and one with a beta thalassemia mutation, he or she is said to carry the beta thalassemia trait.

Because alpha globin is a necessary component of hemoglobin, absence of all functioning alpha globin genes leads to serious medical consequences that begin even before birth.

Hemoglobin consists primarily of iron-bearing proteins called heme groups and moiety globin protein, which together give hemoglobin its ability to carry oxygen.

The genetic defects are subdivided into errors of heme production (porphyria) and those of globin production, known collectively as the hemoglobinopathies.

This occurs in many diseases, including iron deficiency anemia, thalassemia (an inherited disease in which globin chain production is deficient), and anemias associated with chronic infection or disease.

A normal hemoglobin molecule contains two alpha globin molecule contains two alpha globins and two beta globins to make up the complement of 4 globins.

Human adult hemoglobin is actually a composite of four protein chains called globin is actually a composite of four protein chains called globins, knotted around each other.

Since there are four genes (instead of the usual two) to consider when looking at alpha globin gene inheritance, there are several alpha globin types that are possible.