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gigantism

gigantism

gigantism Sentence Examples

  • When pathological GH excess occurs before epiphyseal fusion in the long bone, the condition is known as gigantism.

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  • What causes gigantism and dwarfism among many species arriving on oceanic islands such as the Seychelles?

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  • Overproduction of hGH or IGH-I, or an exaggerated response to these hormones, can lead to gigantism or acromegaly, both of which are characterized by a very large stature.

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  • Gigantism is the result of hGH overproduction in early childhood leading to a skeletal height up to 8 feet (2.5 m) or more.

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  • The somatotropin test also aids in documenting the excess hGH production responsible for gigantism or acromegaly, and confirms underactivity or overproduction of the pituitary gland (hypopituitarism or hyperpituitarism, respectively).

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  • This procedure, also called the glucose loading test, is performed to evaluate excessive baseline levels of hGH and to confirm diagnosis of gigantism in children (and acromegaly in adults).

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  • In a child with excessive hGH levels, failure of suppression indicates anterior pituitary dysfunction and confirms a diagnosis of gigantism (or acromegaly).

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  • If such a tumor develops within the first ten years of life, the result is gigantism (in which growth is accelerated) and not acromegaly.

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  • If the tumor develops after growth has stopped, the result is acromegaly, not gigantism.

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  • If the tumor develops after growth has stopped, the result is acromegaly, not gigantism.

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  • In adults, this condition results in an enlargement of bones; in children, the abnormality results in excessive height and is called gigantism.

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  • This variant is called gigantism, with the additional bone growth causing unusual height.

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  • Gigantism occurs even more rarely, with reported cases in the United States numbering only about 100 by 2004.

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  • Onset of gigantism is usually at puberty, although some cases of toddlers and young children with gigantism have been reported.

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  • The most common cause of acromegaly and gigantism is the development of a noncancerous tumor within the pituitary, called a pituitary adenoma.

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  • Children and adolescents with gigantism show a characteristic lengthening and enlargement of bones, principally of the limbs.

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  • By contrast, the effects of gigantism are typically dramatic, with remarkable changes over a short period of time.

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  • Individuals with acromegaly or gigantism who have diabetes or diabetes-like symptoms should maintain a diet that helps normalize blood sugar levels.

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  • The initial onset of acromegaly or gigantism cannot as of 2004 be prevented.

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  • In individuals with gigantism who are not treated, linear growth can continue unchecked for several decades.

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  • "Gigantism and Acromegaly." eMedicine, July 29, 2004.

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