How to use Enzyme in a sentence
Such an enzyme is the pepsin of the stomach of the higher animals.
These genetic defects are found in infants who are missing a necessary enzyme or protein.
The enzyme in plants which breaks down starch is sometimes called diastase.
But this has not been proved, and hitherto no enzyme has been separated from a pathogenic bacterium capable of forming, by digestive or other action, the toxic bodies from proteids outside the body.
Iron is essential for important enzyme reactions, growth, and maintaining a healthy immune system.Advertisement
I had been working on an enzyme which was called glyceraldehyde phosphate dehydrogenase.
A common way in which proteins are degraded is by ' enzyme digestion ' .
Zinc is an essential cofactor for the important antioxidant enzyme Superoxide Dismutase.
During germination the barley secretes the enzyme diastase which makes the starch in the barley soluble, thus preparing it for conversion into sugar.
The enzyme forms a dimer in the crystal structure.Advertisement
I found the enzyme site very rewarding to read.
Chewable lactase enzyme tablets are also available.
Alactasia-A rare inherited condition causing the lack of the enzyme needed to digest milk sugar.
Iron is a mineral found in the bloodstream that is essential for growth, enzyme development and function, a healthy immune system, energy levels, and muscle strength.
Magnesium-assists in the utilization of calcium and potassium, and functions in enzyme reactions to produce energy.Advertisement
The activity of an enzyme (glutathione peroxidase) in platelets (small blood cells essential in blood clotting) may be evaluated to assess selenium status.
The maturation process depends on an enzyme called Bruton's agammaglobulinemia tyrosine kinase (Btk).
In the early 2000s, it is recommended for CAH children with little or no enzyme activity and can be accomplished by laparoscopy.
This in turn depletes your body's enzyme function which is also needed for your brain, heart, muscles, lungs and more.
It is always best to avoid scratching mosquito bites, as spreading the enzyme fluids across the surface of the skin may cause a brutal hive outbreak or a full blown allergic attack that may require medical treatment.Advertisement
She had been born with a defective version of the gene that normally makes the essential enzyme adenosine deaminase (ADA ).
Saliva contains the enzyme amylase, which breaks down starchy carbohydrate foods into simpler sugars that can be absorbed into your body.
It also contains the enzyme salivary amylase which starts to digest starch into glucose.
Pharmacologic treatment for herpesvirus infections has targeted the virus-specific enzyme, thymidine kinase (TK ), with nucleoside analogs.
The in vitro results showed that CYP3A4 was the major human P450 enzyme catalyzing the biotransformation of imatinib.Advertisement
This enzyme catalyzes the conversion of angiotensin I to angiotensin II in blood plasma and in vascular endothelial tissues and degrades bradykinin.
The outer layer (the mesophyll) fixes CO2 using the enzyme PEP carboxylase to form 4-carbon organic acids.
This carbon-fixing reaction is catalyzed by the enzyme ribulose bisphosphate carboxylase, always known as rubisco.
In Year 11 all the students undertake an investigation into the activity of the enzyme catalase.
We will review enzyme catalysis using the catalytic triad of proteases.Advertisement
Block that enzyme About one third of the dry weight of green tea leaves is made up of a flavonoid called catechin.
Toxic substances may disturb normal cell function, damage cell membranes, interfere with enzyme and immune systems and RNA and DNA activity.
For example, the enzyme cellulase breaks down cellulose, an insoluble polymer, which makes up a major part of plant tissues.
They are nerve poisons, inhibiting the enzyme cholinesterase, which can have severe effects on the central nervous system.
In the late 1930s Max Perutz used the technique to study hemoglobin and the enzyme chymotrypsin.Advertisement
The enzyme DMSP-lyase, found in algae and some bacteria, mediates the cleavage of DMSP to DMS and acrylic acid.
Many of these proteins are also cleaved by proteases, and these enzyme activities are targets of drugs that stop invasion.
By stopping this enzyme working, ACE inhibitors reduce the constriction of the blood vessels.
A small group of dehydrogenases including succinate dehydrogenase (an enzyme in the citric acid cycle) produce FADH 2 rather than NADH.
Display Answer Question 3 The enzyme succinate dehydrogenase is involved in the Kreb's cycle of cellular respiration.Advertisement
This enzyme modifies the host hormone ecdysone to render it inactive.
Each reaction is catalyzed by an enzyme known as a dehydrogenase.
Because of its content of proteolytic enzyme, the kiwi fruit is a potential cause of contact dermatitis.
Reactions to lactose are due to a deficiency of the enzyme lactase, which the body needs in order to digest lactose.
The enzyme absorbs nitrogen which in turn has lowered the air pressure.Advertisement
This enzyme is elevated in bacterial and fungal meningitis, malignancy, and subarachnoid hemorrhage.
These children can often drink milk that has had this enzyme introduced into the product.
Tyrosinase-An enzyme in a pigment cell which helps change tyrosine to dopa during the process of making melanin.
Enzyme replacement therapy is being explored.
The genetic defect causes a deficiency of the enzyme glucocerebrosidase that is responsible for breaking down a certain type of fat and releasing it from fat cells.Advertisement
For those who are sensitive to even very small amounts of lactose, the lactase enzyme supplement is available without a prescription.
Since the cause of the enzyme deficiency leading to carbohydrate intolerance is unknown, there is no way to prevent this condition.
They participate in all enzyme reactions in the body and help in the assimilation and use of vitamins and other nutrients.
The protoplasm appears to be able also to bring about thc change without secreting any enzyme.
It has since been shown by Buchner and Albert that yeast-cells which have been killed by alcohol and ether, or with acetone, still retain the enzyme.
Acetaldehyde still needs to be broken down into sugars and whatnot by the enzyme acetaldehyde still needs to be broken down into sugars and whatnot by the enzyme acetaldehyde dehydrogenase.
Figure 1. Spectral changes spaced a minute apart during enzyme catalysis in crystals of E. coli amine oxidase.
The usual approach is to investigate the effect of the enzyme amylase on the breakdown of starch solution at various temperatures.
The enzyme DNA polymerase joins the new nucleotides to each other by strong covalent bonds, forming the sugar-phosphate backbone.
Normal blood basophils express only trace amounts of the enzyme.
Inhibition of CYP2D6 may lead to increased plasma concentrations of co-administered drugs metabolized by this enzyme.
With conventional oral and intravenous administration of CPA, the drug is activated in the liver by the P450 enzyme.
Benefits Used by the body to activate a potent antioxidant enzyme which can help protect the body against cancer.
Levels of serum angiotensin-converting enzyme were within normal limits.
Both compounds are inhibitors of the HCV protease enzyme, which the virus uses to replicate itself.
The enzyme catalyzes the first step in carbon dioxide fixation in these plants and good inhibitors might be effective herbicides.
For example in our biology students we tried to find out about enzyme activity in sheep's liver and will be dissecting a frog.
Its acts by inhibiting the enzyme, glutamine synthetase, which converts the essential amino acid, glutamic acid to glutamine synthetase, which converts the essential amino acid, glutamic acid to glutamine.
Glutamine is readily synthesized from glutamate and ammonium ions by the enzyme glutamine is readily synthesized from glutamate and ammonium ions by the enzyme glutamine synthetase.
N-acetylcysteine (NAC) - an amino acid that naturally stimulates your body to produce glutathione - is a powerful antioxidant enzyme.
This dosage induces optimum levels of the antioxidant enzyme glutathione peroxidase in the lungs.
Streptococcus produce the enzyme hyaluronidase which hydrolyses hyaluronic acid, a polysaccharide component responsible for binding cells together.
This is the reason why some subcutaneous injections and drugs in creams or ointments include a small amount of the enzyme hyaluronidase.
When honey is diluted, a special enzyme the bees have added produces hydrogen peroxide, a well-known antibiotic.
The plant is designed for a two-step dilute acid hydrolysis process and a combination with enzyme hydrolysis.
The plots show the ligand's Trp 252 residue nestling in the highly hydrophobic specificity pocket of the enzyme's active site.
Rotavirus can be detected by electron microscopy, enzyme immunoassay (EIA ), or PCR.
However their work had reached an impasse be cause they were not able to produce enough enzyme for use in further studies.
My research involved testing the reactivity and enzyme inhibition properties of novel compounds.
Often, a plant intron is introduced into the code for the bacterial enzyme to enhance transport of the message from nucleus to cytoplasm.
The active site of an enzyme will only be able to operate on one type of optical isomer.
Why is glucose syrup refined to remove the enzyme, glucose isomerase?
The enzyme glucose isomerase is immobilized onto beads of calcium alginate in a glass column.
The study product is an adenovirus derived vector which contains the gene for the enzyme thymidine kinase (TK ).
However, it is rare that relationships in biology, including enzyme kinetics, follow a straight line.
Well, now we have to go into enzyme kinetics.
In order for lactose to be digested, the body produces an enzyme called lactase.
People with fructose intolerance do not have the enzyme 1-phosphofructaldolase (also called aldolase B enzyme and fructose 1-phosphate aldolase).
This enzyme is necessary for the absorption of fructose.
There is no cure for hereditary fructose intolerance, since the enzyme needed to process fructose is missing at birth.
This form of EDS is caused by a change in the PLOD gene on chromosome 1, which encodes the enzyme lysyl hydroxylase.
An amniocentesis may be performed in which fetal cells are removed from the amniotic fluid and enzyme activity is measured.
This form of EDS is caused by a change in the enzyme called procollagen I N-terminal peptidase.
Some children may lack a specific enzyme needed to metabolize certain foods.
Inborn error of metabolism-One of a group of rare conditions characterized by an inherited defect in an enzyme or other protein.
Alterations in enzyme levels, tissue abnormalities, and organ malfunction may be followed by illness and death.
The hair converts tyrosine with the help of an enzyme called tyrosinase.
In most of these disorders, the body does not produce a certain enzyme, or specialized chemical.
Some of these disorders can be controlled with changes in the diet, medications, or enzyme supplements.
Without this enzyme, fatty compounds start to line the blood vessels.
Gaucher disease may be suspected, based on symptoms, and is confirmed with a blood test for levels of the deficient enzyme.
The symptoms of Gaucher disease can be stopped and even reversed by treatment with enzyme replacement injections.
Two enzyme drugs available are alglucerase (Ceredase) and imiglucerase (Cerezyme).
Krabbe's disease is caused by a deficiency of the enzyme galactoside beta-galactosidase.
The different types seem to be related to the activity level of the enzyme sphingomyelinase.
It is due to a deficiency of phytanic acid hydroxylase, an enzyme that breaks down a fatty acid called phytanic acid.
Tay-Sachs disease (TSD) is a fatal condition caused by a deficiency of the enzyme hexosaminidase A (Hex-A).
Wolman's disease is caused by a genetic defect with a recessive pattern of inheritance that results in a deficiency of an enzyme that breaks down cholesterol.
Canavan disease is caused by the lack of an enzyme called aspartoacylase.
Anti-inflammatories such as bromelain (a proteolytic enzyme from pineapples) and tumeric (Curcuma longa) may also be helpful.
These medications block the production of an enzyme that aids in the production of acid.
Adenosine deaminase (ADA)-An enzyme that is lacking in a specific type of severe combined immunodeficiency disease (SCID).
The discovery of individual enzyme deficits resulted in a reclassification of some of the MPS disorders.
As a result, either no enzyme is produced, or the amount produced is inadequate.
Although MPS are all inherited disorders, each type is caused by a deficiency of one particular enzyme involved in breaking down GAGs.
Three conditions, Hurler, Hurler-Scheie, and Scheie syndromes, are caused by a deficiency of this enzyme.
Hunter syndrome is caused by a deficiency of the enzyme iduronate-2-sulphatase.
Therefore, enzyme analysis is used to determine the specific MPS disorder.
Enzyme analysis often cannot accurately determine if an individual is a carrier for an MPS disorder, because the enzyme levels in individuals who are not carriers overlaps the enzyme levels seen in those individuals who are carrier for MPS.
Tay-Sachs disease is a genetic disorder caused by a missing enzyme that results in the accumulation of a fatty substance in the nervous system.
In Tay-Sachs disease, the enzyme necessary for removing excess gangliosides is missing.
Without this enzyme, gangliosides cannot be broken down.
Each step of the chemical pathway is directed by its own task-specific protein, called an enzyme.
As a heme precursor molecule moves through each step, an enzyme modifies the precursor in some way.
These precursors accumulate at the stage of the enzyme defect, causing an array of physical symptoms in an affected child.
Each type of porphyria corresponds with a specific enzyme defect and an accumulation of the associated precursor.
The underlying cause of all porphyrias is a defective enzyme important to the heme biosynthesis pathway.
In virtually all cases of porphyria, an inherited factor causes the enzyme's defect.
The specific symptoms of each porphyria vary based on which enzyme is affected and whether that enzyme occurs in the liver or in the bone marrow.
This enzyme deficiency is caused by mutations in the ferrochelatase gene (FECH) located at 18q21.3.
Making this determination yields a strong indicator of which enzyme in the heme biosynthesis pathway is defective; which, in turn, allows a diagnosis of the particular type of porphyria.
Certain enzymes, such as porphobilinogen deaminase (the defective enzyme in AIP), can be easily extracted from red blood cells; other enzymes, however, are less readily collected or tested.
Basically, an enzyme test involves adding a certain amount of the enzyme to a test tube that contains the precursor it is supposed to modify.
If a modified precursor is produced, the test indicates that the enzyme is doing its job.
The rate at which the modified precursor is produced can be compared to a standard to measure the efficiency of the enzyme.
Many doctors, however, skip this test if the child has the typical heliotrope rash, shows signs of muscle weakness during the physical examination, and has high muscle enzyme levels in the blood test.
A muscle biopsy is necessary, however, if the child has the heliotrope rash but normal enzyme levels.
Some doctors may order a magnetic resonance imaging (MRI) test in order to evaluate the presence of inflammation in the muscles of children with normal muscle enzyme levels in their blood.
By definition, a peroxisome must contain catalase, which is an enzyme that breaks down hydrogen peroxide.
Failure to thrive is a common characteristic of patients with peroxisomal disorder, along with an enlarged liver, abnormalities in liver enzyme function, and loss of fats in stools (steatorrhea).
In X-ALD there is a deficiency in the enzyme that breaks down VLCFAs, which then accumulate in myelin and the adrenal glands.
Enzyme replacement therapies, including enzyme infusion, transplantation, and gene therapy, may hold promise for future advances in the treatment of these disorders.
Retrovirus-A family of RNA viruses containing a reverse transcriptase enzyme that allows the viruses' genetic information to become part of the genetic information of the host cell upon replication.
Regardless of the specific cause of DIC, the results are a malfunction of thrombin (an enzyme) and prothrombin (a glycoprotein), which activate the fibrinolytic system, releasing clotting factors in the blood.
Reactive hypoglycemia can be triggered by enzyme disorders and by gastric bypass surgery.
This condition is due to a deficiency of the enzyme trypsin and other digestive enzymes produced in the pancreas.
People with celiac disease may also experience lactose intolerance because they do not produce enough of the enzyme lactase, which breaks down the sugar in milk into a form the body can absorb.
Tay-Sachs disease-An inherited disease caused by a missing enzyme that is prevalent among the Ashkenazi Jewish population of the United States.
One form of LGMD is caused by defects in the gene for a muscle enzyme, calpain.
Phenylketonuria (PKU) is a rare metabolic disorder caused by a deficiency in the production of the hepatic (liver) enzyme phenylalanine hydroxylase (PAH).
This enzyme converts (metabolizes) the amino acid called phenylalanine into another amino acid, tyrosine.
Mutations in the PAH gene prevent the liver from producing adequate levels of the PAH enzyme needed to break down phenylalanine.
In more detail, PKU mutations can involve many different types of changes, such as deletions and insertions, in the DNA of the gene that codes for the PAH enzyme.
A carrier does not display any symptoms of the disease because the carrier's liver produces normal quantities of the PAH enzyme.
Other techniques used to diagnose a chlamydial infection are enzyme immunoassays, serum antibody tests, and DNA probes.
This is usually due to deficiency of an enzyme needed for digestion.
Congenital deficiency is caused by an enzyme defect present at birth.
Alactasia is a very rare congenital condition and the result of a genetic defect that causes the complete absence of lactase, the enzyme needed to digest milk sugar.
Primary deficiency is caused by an enzyme defect developed over time.
Because of the uneven distribution of enzyme deficiency based on race and ethnic heritage, especially in lactose intolerance, genetics are believed to play a role in the cause of primary carbohydrate intolerance.
Bruton's agammaglobulinemia tyrosine kinase (Btk)-An enzyme vital for the maturation of B cells.
Biochemical testing-Measuring the amount or activity of a particular enzyme or protein in a sample of blood or urine or other tissue from the body.
Beta-lactamase-An enzyme produced by some bacteria that destroys penicillins.
Persons with galactosemia either have very low levels of or are entirely lack the enzyme that assists the body in breaking down galactose.
This enzyme is called galactose-1-phosphate uridyl transferase (GALT).
The GALT enzyme enables the body to break down galactose into glucose for energy.
The severity of the disease may vary from person to person, because some individuals with galactosemia have higher levels of this enzyme than do others.
Individuals with the classic type of galactosemia lack the enzyme activity necessary to metabolize galactose.
Individuals with the Duarte variant have approximately 5-20 percent of the enzyme activity necessary to metabolize this sugar and often do not have signs or symptoms of galactosemia.
The physician may also perform enzyme studies on or look for the presence of "reducing substances" in the child's urine, look for ketones in the urine, and measure enzyme activity in the red blood cells.
Congenital adrenal hyperplasia (CAH) is a form of adrenal insufficiency in which 21-hydroxylase, the enzyme that produces two important adrenal steroid hormones, cortisol and aldosterone, is deficient.
In its most severe form, called salt-wasting (or salt-losing) CAH, where there is a total or near total deficiency of the 21-hydroxylase enzyme, a life-threatening adrenal crisis can occur if the disorder is untreated.
There is also a milder form of CAH in which children have partial 21-hydroxylase enzyme deficiencies (simple virilizing form).
Those with liver disease should monitor enzyme activity carefully while taking DHEA.
This occurs because sufferers lack an important enzyme that is needed to utilize phenylalanine.
Humans and other primates, however, lack the enzyme necessary to synthesize their own.
Studies have indicated that enzyme action is destroyed at temperatures of 118 degrees or greater.
The vegetable contains the protein-digesting enzyme, erepsin.
There is no medical evidence to support the theory that fruit contains any enzyme or chemical that dissolves toxins.
Some people lack an enzyme necessary to digest lactose, the sugar in cow's milk.
Here the enzyme Eco RI is used to sever plasmid DNA which is then re-joined using DNA ligase.
Since photosynthetic light reactions produce ATP, the ATP dependence of RuBisCO activation provides a mechanism for light-dependent activation of the enzyme.
In acute pancreatitis, elevated amylase levels usually parallel levels of another enzyme called lipase.
Human milk contains the enzyme lipase which helps the baby digest milk fat more efficiently.
Luciferase This molecule is an enzyme which reacts with ATP to cleave luciferin, its substrate.
During anaerobic growth, pyruvate is cleaved into formate and acetyl-CoA by the enzyme pyruvate formate lyase (PFL ).
Patients who have a malignancy are also slow to respond to enzyme treatment.
Hence, strong inhibitors of this enzyme may inhibit the metabolism of clarithromycin, resulting in increased plasma concentrations of clarithromycin.
The results show that no single enzyme controls glucose metabolism.
Figure 1. A reversed micelle with enzyme trapped inside.
Some of the recommendations have been used in enzyme nomenclature  .
The enzyme is modulated by adenine and guanine nucleotides, although it is difficult to make much sense of the observed effects.
The polyamines are progressively synthesized by decarboxylation from ornithine by a rate limiting enzyme ornithine decarboxylase (ODC ).
In the experiment with catechol oxidase from bananas, why is sand used to extract the enzyme?
The most notable example of this is in the enzyme cytochrome oxidase.
Using the proteolytic enzyme papain Porter found rabbit IgG was cleaved into three similarly sized pieces.
In the stomach, the gastric gland produces gastric juices that contain the enzyme pepsin that breaks down proteins.
Acid and the digestive enzyme pepsin are secreted here.
There is a third natural antioxidant enzyme called, glutathione peroxidase which also reduces hydrogen peroxide to water.
The hydrogen peroxide in honey is produced by an enzyme in the honey.
People who lack the enzyme to convert phenylalanine to tyrosine are not able to metabolize phenylalanine normally.
The baby is unable to make an enzyme, phenylalanine hydroxylase, which converts phenylalanine hydroxylase, which converts phenylalanine to tyrosine.
Classical PKU is caused by a deficiency of the liver enzyme phenylalanine hydroxylase, which converts the amino acid phenylalanine to tyrosine.
This layer is removed by the action of a fungal acid phosphatase enzyme.
Investigate the nature of the inhibition using the enzyme phosphatase and the inhibitors phosphate and iodine.
The double helix of the DNA ' unzips ', and the enzyme DNA polymerase makes a copy using the separated strands as templates.
Such experiments have been supported fully by experiments with synthetic polypeptides and, more recently, a synthetic enzyme.
Recent scholarship has proffered the theory that his condition was occasioned by an enzyme deficiency that leads to the inherited disease porphyria.
Use of the restriction enzyme Eco RI was used to distinguish between sheep and goat pox isolates.
The Kiwi fruit already contains a lot of a special enzyme called a proteinase.
The enzyme will now be constructed using AMBER, and the active site treated quantum mechanically.
An enzyme is a highly active protein that accelerates a chemical reaction.
Two of the compounds also led to a fourfold boost in production of a detoxifying enzyme called quinone reductase in mouse liver cells.
Saw Palmetto inhibits the enzyme 5-alpha reductase, which in turn reduces the amount of DHT produced.
Substrate binding to this site is thought to affect enzyme activity by altering the relative positions of the two subunits of ribonucleotide reductase.
Low blood pressure causes a release of the enzyme renin from the kidney.
This would not have been possible without enzyme replacement therapy.
Now transfer 20 µl of DNA to each of the TWO pink tubes containing a restriction enzyme.
These systems are also an excellent model of how enzyme specificity is controlled in a more general sense.
An enzyme in endothelial cells called JNK is involved in causing increased stickiness by some inflammatory agents.
Bees produce an enzyme which splits sucrose (from nectar) into glucose and fructose.
The drug seems counteract production of an enzyme called superoxide that is induced by interleukin-2 and may result in the low blood pressure.
This enzyme converts dangerous superoxide free radicals to the less dangerous hydrogen peroxide.
The anti-aging enzyme superoxide dismutase (SOD) is one of these.
Its acts by inhibiting the enzyme, glutamine synthetase, which converts the essential amino acid, glutamic acid to glutamine.
Glutamine is readily synthesized from glutamate and ammonium ions by the enzyme glutamine synthetase.
The majority of human tumors stabilize their telomere lengths by activation of the enzyme telomerase.
In the male fetus, an enzyme, 5 alpha reductase, converts testosterone to dihydrotestosterone.
Acetate is subsequently transferred to a cysteine thiol of the Condensing Enzyme domain.
This entails investigating mitochondrial glutathione and protein thiols and the enzyme systems involve in their metabolism.
Another target that is attracting some interest is an enzyme called farnesyl protein transferase.
In order for the carbamate to reform, the enzyme must undergo transition to the open conformation.
For functional studies we reconstitute purified enzyme into liposomes, to analyze coupling between electron transfer and proton translocation.
Removal of part of the peptide using the enzyme trypsin restores the native structure of the virus.
Biologically, melanin production is controlled by the action of the enzyme tyrosinase.
Tyrosine is converted into DOPA by the enzyme tyrosine is converted into DOPA by the enzyme tyrosine hydroxylase.
The test is based on the capacity of H. pylori to secrete the enzyme urease, which hydrolyses urea to ammonia and carbon dioxide.
According to Buchner the fermentative activity of yeast-cell juice is not due to the presence of living yeast cells, or to the action of living yeast protoplasm, but it is caused by a soluble enzyme.
These investigators considered that differences of this nature cannot be explained by the theory that it is a soluble enzyme, which brings about the alcoholic fermentation of sugar.
It is an obvious inference that if a small quantity of a substance can affect the development of an entire organ it probably acts after the manner of an enzyme.
This completely destroys the ferment or enzyme, and renders it possible to conserve the tea in what is really nearer its natural form than the black tea that is so well known to the consumer.
It tells you a bit about the catalytic activity of the enzyme and its cofactor Pyridoxal Phosphate.
Certain combinations of minerals, herbs and vitamins bind with the 5-alpha reductase enzyme to stop it converting testosterone to dihydrotestosterone.
This technique is rapid and involves little more work than restriction enzyme analysis once the site of the mutation is known.
A restriction enzyme cuts DNA when it encounters a specific sequence of bases.
Reverse transcriptase is an important enzyme used in making new virus.
It is isolated from the micro-organism, Serratia E15, an enzyme that is naturally present in the silkworm intestine.
One approach is to change the natural substrate specificity of an enzyme through mutagenesis.
The steady-state concentration depends upon the enzyme reaction kinetics, which must be rapid.
This article compares the traditional statistical approach to our understanding of enzyme function with that of the opposing structuralist view.
However, the substrate for the enzyme was unknown.
The enzyme is found in most types of tumor cells but not in healthy cells, indicating the potential of telomerase inhibitors in chemotherapy.
However, the telomerase enzyme can build the telomeres up again, extending the life of the cell.
This enzyme is believed to be involved in the biosynthesis of isoleucine in methanogens and possibly other species lacking threonine dehydratase.
Both drugs act by terminating the growth of the DNA chain and inhibiting the reverse transcriptase enzyme of HIV.
It performs the conversion by an enzyme called tryptophan hydroxylase.
Tyrosine is converted into DOPA by the enzyme tyrosine hydroxylase.
The project will start by looking at the vaccinia type I topoisomerase enzyme.
Papain Papain, an enzyme extract of papaya, was associated with increased warfarin activity in one patient.
Most Westerners eat far too much protein, which disrupts liver enzyme activity.
In addition, these babies were found to have 22 percent lower tryptophan hydroxylase level, which is the enzyme that produces serotonin, and the levels of binding in serotonin receptors were 50 percent lower in the babies who died of SIDS.
There are organic versions of jarred baby food available, but they are not the equivalent of fresh enzyme rich raw foods.
Don't dry bras in a dryer; rotate bras from day to day to allow each bra time to return to its original fit, and pre-treat milk stains with a laundry detergent that contains an enzyme to dissolve the stains.
Be sure to tell the cleaner that you used an enzyme cleaner to rid the carpet of the odor.
I would also clean the area thoroughly with an enzyme cleaner.
The first step is going to be a thorough cleaning of the area with an enzyme cleaner.
Simple Solution Cat Stain and Odor Remover is a bacterial enzyme cleaner with a clean, citrus scent, and it is safe to use around children and pets.
Enzyme cleaners are made from formulas containing special ingredients that actually eat the crystals and bacteria present in cat urine.
Make sure to follow the directions on any commercial enzyme cleaner you choose.
Always make sure to thoroughly saturate the area with the enzyme cleaner.
If you do not have a commercial enzyme cleaner, many pet parents have removed cat urine using common household products including baking soda, hydrogen peroxide, white vinegar and dishwashing detergent.
Saturate the area with a commercial enzyme cleaner or your home made remedy.
In its raw state, fish may have high levels of an enzyme called thiaminase.
Cooking destroys this enzyme and keeps your cat safer.
It is a retrovirus that produces an enzyme that reproduces itself in the cells it infects.
The journal Atherosclerosis reports that pomegranate juice reduces angiotensin converting enzyme activity and thus lowers blood pressure.
Some blood pressure medications, called ACE (angiotensin converting enzyme) inhibitors, already work in a similar fashion through chemical means.
Cayenne is naturally high in sulfur compounds that the body uses to create hydrogen sulfide in the lining of the blood vessels via an enzyme called CSE (cystathionine gamma-lyase).
If you are lacking the enzyme lactase, you will not be able to digest the milk sugar lactose.
Lactase is the enzyme that your body needs to successfully digest milk and dairy products.
Rennet is an enzyme used to coagulate cheese, helping it make the transformation from liquid milk form to a solid.
Raw foods, on the other hand, are filled with enzymes, and therefore do not deplete the enzyme stores during digestion.
The thing that makes mildew destructive is an enzyme it secretes.
This enzyme decomposes organic matter and uses it as food.
At this point, add the pectic enzyme and yeast nutrient.
Phenylketonuria-A condition caused by a genetic error of the body's metabolism, characterized by the absence of phenylalanine hydroxylase (an enzyme that converts phenylalanine into tyrosine).
The enzyme lactase, which is normally produced by cells lining the small intestine, breaks down lactose into substances that can be absorbed into the bloodstream.
However, individuals who are mildly or moderately deficient in the production of the lactase enzyme may not exhibit symptoms of lactose intolerance.
While rare, some children are also born unable to produce the enzyme.
In the early 2000s, researchers have developed a chewable lactase enzyme tablet.
Lactase-The enzyme produced by cells that line the small intestine that allows the body to break down lactose.
Hereditary fructose intolerance is a metabolic disorder in which the small intestine cannot process fructose (fruit sugar) into a source of energy because of an enzyme deficiency that prevents fructose absorption.
An enzyme is a substance that acts as a catalyst to produce chemical changes without being changed itself.
When people with fructose intolerance ingest fructose or sucrose (cane or beet sugar, table sugar), complicated chemical changes occur in the body due to the absence of the enzyme needed to process these sugars.
A 570 bp DNA fragment amplified from the capsid protein gene was digested with Ava II restriction enzyme and separated by gel electrophoresis.
Phenylketonuria (PKU)-A rare, inherited, metabolic disorder in which the enzyme necessary to break down and use phenylalanine, an amino acid necessary for normal growth and development, is lacking.
A blood test that measures levels of the enzyme lactate dehydrogenase (LDH) can help predict the likelihood of a specific patient's survival.
One promising line of PKU research involves the synthesis (manufacturing) of a new type of enzyme that can break down phenylalanine in food consumed by the patient.
Lactose intolerance is the most common of all enzyme deficiencies, and an estimated 30-50 million Americans have this condition.
Usually they are named by adding ase to the name of the substance they act on (for example, lactase is the enzyme needed to process lactose).
In the mouth, cooked starch is broken down to a disaccharide by amylase, an enzyme in the saliva.
The severity of the symptoms depends upon the extent of the enzyme deficiency, and ranges from a feeling of mild bloating to severe diarrhea.
An over-the-counter product marketed by the brand name Beano contains the enzyme alpha-galactosidase that works with the body's digestive system to break down complex carbohydrates into simple sugars that are easily digested.
Another type of CAH is characterized by only a slight deficiency in production of the 21-hydroxylase enzyme (nonclassic or late-onset form), in which symptoms occurs later in childhood or during young adolescence.
This is usually accomplished through drug therapy, although surgery may be an alternative for children with little or no enzyme activity.
Treatment results must be monitored carefully, because of large individual variations in enzyme deficiency in children with CAH.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency-A sex-linked hereditary disorder in which the body lacks an enzyme that normally protects red blood cells from toxic chemicals.
In particular, it seems to prevent the enzyme P-450 from doing its job to break down medications in the intestinal tract.
This same research points to an enzyme deficient diet as a contributor to children and teens being overweight.
Pineapple contains bromelain, which is an enzyme that breaks down protein.
What it does claim is to be based on that same chemical reaction theory as the Grapefruit Diet with the magic enzyme burning unwanted fat.
Bromelain is a protease enzyme that digests protein.
A third enzyme, the trypsin of the pancreas, possesses the power of both pepsin and erepsin.
On a successful wither the amount of the tea ferment or enzyme is dependent.
There is present in the seeds an enzyme which rapidly decomposes the oil if the seeds are crushed and kept, setting free a fatty acid and glycerin.
This, like the excretion of the sundew and other insectivorous plants, contains a digestive ferment (or enzyme) which renders the nitrogenous substances of the body of the insect soluble, and capable of absorption by the leaf.
Lea and Miguel further proved that the hydrolysis is due to an enzyme - urase - separable with difficulty from the bacteria concerned.
Considerable differences occur in these latter respects, however, and interesting results were obtained by Beyerinck with mixtures of species possessing different powers of enzyme action as regards carbohydrates.
Fischer found that the enzyme "invertase," which is present in yeast, attacks methyl-d-glucoside but not methyl-l-glucoside.
The digestion of fat or oil has not been adequately investigated, but its decomposition in germinating seeds has been found to be due to an enzyme, which has been called lipase.
It has been ascertained that in many cases this decomposition is effected by the secretion of an enzyme, which has been termed zymase.
In the case of diphtheria Sidney Martin obtained toxic albumoses in the spleen, which he considered were due to the digestive action of an enzyme formed by the bacillus in the membrane and absorbed into the circulation.
Dubois (1886), who considers that the luminosity is due to the influence of an enzyme in the cells of the organ upon a special substance in the blood.
Although the action of zymase may be regarded as mechanical, the enzyme cannot be produced by any other than living protoplasm.
It occurs free in bitter almonds, being formed by an enzyme decomposition of amygdalin.
In 1894 and 1895, Fischer, in a remarkable series of papers on the influence of molecular structure upon the action of the enzyme, showed that various species of yeast behave very differently towards solutions of sugars.
Another enzyme, rennet, which in the animal body is proteolytic, is frequently met with in plants, but its function has not been ascertained.
That such enzymes are formed in the protoplasm is evident from the behaviour of hyphae, which have been observed to pierce cell-membranes, the chitinous coats of insects, artificial collodion films and layers of wax, &c. That a fungus can secrete more than one enzyme, according to the materials its hyphae have to attack, has been shown by the extraction of diastase, inulase, trehalase, invertase, maltase, raffinase, malizitase, emulsin, trypsin and lipase from Aspergillus by Bourquelot, and similar events occur in other fungi.
The irritation set up by the hatching egg and its resulting larva appears to be the stimulus to development, and net a poison or enzyme injected by the insect.