Dmd Sentence Examples
There is also a slightly elevated creatine kinase level in females carrying a DMD disease allele.
McDaniel, DMD is board certified with the ABDSM and he works with the Snoring and Sleep Apnea Treatment Center in Wauwatosa.
Duchenne muscular dystrophy (DMD), which affects young boys, causing progressive muscle weakness, usually beginning in the legs.
Several of the muscular dystrophies, including DMD, BMD, CMD, and most forms of LGMD, are due to defects in the genes for a complex of muscle proteins.
Both DMD and BMD are caused by flaws in the gene for the protein called dystrophin.Advertisement
The flaw leading to DMD prevents the formation of any dystrophin, while that of BMD allows some protein to be made, accounting for the differences in severity and onset between the two diseases.
X-linked diseases include DMD, BMD, and EDMD.
Some female carriers of DMD suffer a mild form of the disease, probably because their one unaffected gene copy is shut down in some of their cells.
As many as one-third of the cases of DMD are due to new mutations that arise during egg formation in the mother.
Later on, the boy with DMD will push his hands against his knees to rise to a standing position, to compensate for leg weakness.Advertisement
About the same time, his calves will begin to swell, though with fibrous tissue rather than with muscle and feel firm and rubbery; this condition gives DMD one of its alternate names, pseudohypertrophic muscular dystrophy.
The most serious weakness of DMD is weakness of the diaphragm, the sheet of muscles at the top of the abdomen that perform the main work of breathing and coughing.
Young men with DMD often live into their twenties and beyond, provided they have mechanical ventilation assistance and good respiratory hygiene.
About one third of boys with DMD experience specific learning disabilities, including trouble learning by ear rather than by sight and trouble paying attention to long lists of instructions.
Though the progression of symptoms may parallel that of DMD, the symptoms are usually milder, and the course more variable.Advertisement
A severe childhood form is similar in appearance to DMD but is inherited as an autosomal recessive trait.
Accurate genetic tests are available for DMD, BMD, DM, several forms of LGMD, and EDMD.
Childhood-onset LGMD is often mistaken for the much more common DMD, especially when it occurs in boys.
Prednisone, a corticosteroid, has been shown to delay the progression of DMD somewhat, for reasons that as of 2004 are still unclear.
Full-leg braces may be used in DMD to prolong the period of independent walking.Advertisement
Scoliosis surgery is often needed in DMD but much less often in other muscular dystrophies.
Surgery is recommended at a much lower degree of curvature for DMD than for scoliosis due to other conditions, since the decline in respiratory function in DMD makes surgery at a later time dangerous.
The weakness in the throat muscles seen especially in OPMD and later DMD may necessitate the use of a gastrostomy tube, inserted in the stomach to provide nutrition directly.
Duchenne muscular dystrophy (DMD)-The most severe form of muscular dystrophy, DMD usually affects young boys and causes progressive muscle weakness, usually beginning in the legs.
Two experimental procedures aiming to cure DMD have attracted a great deal of attention.Advertisement
The expected life span for a male with DMD has increased significantly since the 1970s.