Craniosynostosis Sentence Examples

Craniosynostosis is one of a diverse group of deformities in the head and facial bones called craniofacial anomalies.

An infant or child with craniosynostosis has improperly fused or joined bones (sutures) in the skull.

When children with craniosynostosis also show other body deformities, their condition is called syndromic craniosynostosis.

Primary craniosynostosis occurs when one or more of an infant's sutures (where skull bones meet) fuse prematurely.

Secondary craniosynostosis results when one or more of an infant's sutures fuse prematurely as a result of lack of proper brain growth.

The form of craniosynostosis depends on the suture or sutures that are affected.

Plagiocephaly is the most common form of craniosynostosis.

This type of craniosynostosis involves fusion of the metopic suture that runs from the top of the head toward the nose, which can create a ridge running down the forehead and gives the front of the head a wedge-shaped effect.

Positional nonsyndromic plagiocephaly is a form of craniosynostosis.

Craniosynostosis occurs in one out of 2,000 live births in the United States.

Of those affected, 2-8 percent have primary craniosynostosis and the remaining cases are secondary craniosynostosis.

Sagittal craniosynostosis is the most common type of single suture craniosynostosis.

Although sagittal craniosynostosis mostly occurs by chance, about 2-6 percent of cases are considered to be inherited.

As of 2004 the exact cause of craniosynostosis is not understood.

Craniosynostosis usually occurs by chance (sporadic).

Genetic abnormalities such as craniosynostosis are described by the type of chromosome that carries the abnormal gene and whether the gene is recessive or dominant.

When both parents are carriers, there is a 25 percent chance that each child born will inherit the abnormal gene and develop craniosynostosis.

When one parent has the abnormal gene and the other parent has normal genes, craniosynostosis can still result.

Other genetic syndromes, such as Crouzon syndrome, Apert syndrome, and Pfeiffer syndrome, are associated with craniosynostosis.

The physical symptoms of craniosynostosis depend on the sutures affected.

Craniosynostosis is a progressive condition that must be treated.

The skull and facial asymmetry associated with craniosynostosis are frequently observed by an infant's pediatrician or family physician.

Craniosynostosis may be present at birth or may be observed later when a child has delays in neurological development.

Craniosynostosis may be suspected when an infant has an abnormally shaped head or a small bony ridge along the skull in various locations.

Family history of craniosynostosis or other craniofacial abnormalities also will be discussed.

If craniosynostosis is suspected, an x ray or a CT scan of the child's skull will be taken.

Mutations in what are called fibroblast growth factor receptors (FGR1, 2, and 3) and the transcription factor TWIST are responsible for several types of craniosynostosis.

Deformational plagiocephaly (positional molding)-A form of craniosynostosis in which the head is misshapen, the result of constant pressure to the same area of the head.

Pfeiffer syndrome-This condition includes craniosynostosis, shallow eye sockets, underdevelopment of the midface, short thumbs and big toes, and possible webbing of hands and feet.

Plagiocephaly-A form of craniosynostosis that involves fusion of the right or left side of coronal suture.

For most children with craniosynostosis, facial and skull deformity will be obvious and may be expected to worsen as the child grows.

It is important to detect and treat craniosynostosis early.

Untreated craniosynostosis will remain the same or worsen as a child grows and can affect a child's mental and physical development.

A child with craniosynostosis will require ongoing medical evaluations to ensure that the brain, skull, and facial bones are developing properly.

As of 2004 there was no known prevention for craniosynostosis.

Parents who have an increased likelihood of carrying the genes that result in craniosynostosis may seek genetic counseling to better understand inheritance patterns and chances for reoccurrence.

The physical symptoms of an asymmetrical face and head seen when a child has craniosynostosis are readily apparent and may cause the child embarrassment.

In addition, several conditions exist along with craniosynostosis and need to be evaluated.

A child needs to be carefully evaluated when craniosynostosis is present to distinguish between positional plagiocephaly, caused by back sleeping, and other forms of craniosynostosis.

Craniosynostosis must be treated by surgery.

Jimenez, David, et al. "Endoscopy-assisted wide-vertex craniectomy, barrel stave osteotomies, and postoperative helmet molding therapy in the management of sagittal suture craniosynostosis."