Conine sentence example
Piperine, conine, atropine, belladonine, cocaine, hyoscyamine and nicotine have been already synthesized; the constitution of several others requires confirmation, while there remain many important alkaloids - quinine, morphine, strychnine, &c. - whose constitution remains unknown.
Canine is a secondary base, forming a nitroso derivative with nitrous acid, a urethane with chlorcarbonic ester and a tertiary base (methyl conine) with methyl iodide; reactions which point to the presence of the = NH group in the molecule.
Hofmann had shown that conine on distillation with zinc dust gave a-propyl pyridine (conyrine).
The a-propyl piperidine so obtained is the inactive (racemic) form of conine, and it can be resolved into the dextroand laevo-varieties by means of dextro-tartaric acid, the d-conine d-tartrate with caustic soda giving d-conine closely resembling the naturally occurring alkaloid.
It may be obtained by brominating conine, and then removing the elements of hydrobromic acid with alkalis.Advertisement
Methyl conine, C 9 H 19 N or C8H14 N(CH3), is synthesized from conine and an aqueous solution of potassium methyl sulphate at
Conine, gelseminine and sparteine all exert a paralysing effect on the terminations of the motor nerves, to the implication of which the weakened gait and other symptoms are due.