Coarctation sentence example

coarctation
  • Evidence exists that at least some cases of coarctation may be inherited.
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  • Coarctation of the aorta (COA) is a congenital heart defect that develops in the fetus.
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  • In a constricture or coarctation, the sides (walls) of the aorta press together abnormally, impeding the flow of blood.
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  • Approximately 10 percent of newborns with congenital heart disease have symptomatic coarctation of the aorta.
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  • Thirty percent of infants with Turner syndrome, for example, also have coarctation.
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  • On examination of the heart rhythm using a stethoscope, infants with coarctation of the aorta usually have an abnormal "gallop" heart rhythm, and 50 percent of children also have heart murmurs.
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  • A 10 mm Hg (mercury) pressure difference between the upper and lower extremities is diagnostic for coarctation of the aorta.
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  • The site and the extent of coarctation may also be detected using color-flow Doppler ultrasonography (echocardiology).
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  • Color-flow Doppler studies may show a reduced blood flow below the coarctation.
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  • Drug therapy is used first to treat hypertension and heart failure in children and adults who have coarctation of the aorta.
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  • Surgery may be required for infants who have severe coarctation of the aorta and is usually recommended for those who have associated cardiac defects or those infants who do not respond to drug therapy.
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  • Older children and adults are advised to avoid vigorous exercise prior to surgical correction of the coarctation.
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  • Surgery may involve resection of the coarctation segment or opening and patching the aorta where the coarctation occurred.
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  • Approximately half of all infants diagnosed with coarctation of the aorta have no other cardiac defects and respond well to medical management, growing and developing normally.
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  • The average life span of children who have coarctation of the aorta is 34 years of age, reduced primarily due to complications and to the presence of other heart problems.
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  • Women who have an uncorrected coarctation of the aorta have a mortality rate of 10 percent during pregnancy and a 90 percent rate of complications.
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  • Because congenital coarctation of the aorta is unpredicted, parents may be unprepared for the diagnosis and need careful, sensitive medical explanation by the pediatrician or surgeon.
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  • The most common obstruction defects are pulmonary valve stenosis, aortic valve stenosis, and coarctation of the aorta.
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  • In coarctation of the aorta, the aorta is constricted, reducing the flow of blood to the lower part of the body and increasing blood pressure in the upper body.
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  • Defects such as coarctation of the aorta and aortic valve stenosis have the greatest risk of occurring in the child's offspring.
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  • Coarctation of the aorta-A congenital defect in which severe narrowing or constriction of the aorta obstructs the flow of blood.
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  • From 5 to 10 percent of girls with Turner syndrome have a severe constriction of the major blood vessel coming from the heart (coarctation of the aorta).
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  • Because it is so dangerous, experts suggest early screening and surgery for aortic coarctation of the artery in girls with Turner syndrome.
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  • Coarctation of the aorta is present in about 8 to 10 percent of infants born with other congenital heart defects, occurring approximately twice as many males as females.
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