Chromosomal Sentence Examples
However, no excess chromosomal aberrations in circulating human lymphocytes have been observed in patients treated for 8 months.
Overall, the COM concluded that the results from the in vitro chromosomal aberration assays were likely to represent a cytotoxic response.
In addition, chromosomal deletions of up to 2kb were detected at all 14 integrations sites examined.
Comparative genomic hybridization findings showed chromosomal imbalances in 9 of 12 cases of choriocarcinoma.
Chromosomal instability is thought to occur in 85 per cent of all colorectal cancer cases.Advertisement
However, the identification of all chromosomal aberrations in a complex karyotype was often not possible from such patterns.
A Japanese MFS patient was found with complex chromosomal rearrangements.
Where trisomy 18 is caused by an unbalanced chromosomal translocation, chromosomal analysis should be carried out on both parents.
Alternatively a gene can be selected by chromosomal location or by sequence homology using a customized BLAST search.
If retardation is caused by chromosomal or other genetic disorders, it is often apparent from infancy.Advertisement
Down syndrome-A chromosomal disorder caused by an extra copy or a rearrangement of chromosome 21.
Individuals with A-T have an increased frequency of spontaneous breaks in their chromosomes as well as an increased frequency of chromosomal rearrangements.
These chromosomal abnormalities often occur close to genes that control the function of white blood cells, such as immunoglobulins and T-lymphocytes.
The frequency of chromosomal breaks is increased when T-lymphocytes are exposed to x rays in the laboratory, and this sensitivity to ionizing irradiation forms the basis for a specialized A-T diagnostic test.
People who have idiopathic type 1 diabetes also experience beta cell destruction, but it is due to a chromosomal abnormality or an unknown cause rather than any autoimmune process.Advertisement
Turner syndrome is a chromosomal abnormality occurring only in females in whom one of the X chromosomes is missing or defective.
Possible causes that center on the fetus rather than the mother include chromosomal abnormalities, genetic and other syndromes that impair skeletal growth, and defects of the placenta or umbilical cord.
The leading cause of infant mortality is congenital malformations, deformations and chromosomal abnormalities with a rate of 20.2 percent.
Since additional congenital defects preclude prenatal surgery, amniocentesis or chorionic villi sampling (CVS) are used to check for chromosomal abnormalities in the fetus.
Approximately 5 to 8 percent of individuals with retinoblastoma possess a chromosomal abnormality involving the RB1 gene that can be detected by looking at their chromosomes under the microscope.Advertisement
If this type of chromosomal abnormality is detected in a child, then analysis of the parents' chromosomes should be performed.
If one of the parents possesses a chromosomal abnormality, then they are at higher risk for having other offspring with retinoblastoma.
Usually, however, a chromosomal abnormality is not detected in a child with retinoblastoma.
An amniocentesis or chorionic villus sampling can be used to obtain fetal cells which can be analyzed for the RB1 gene change/deletion or chromosomal abnormality.
Children with abdominal wall defects may need additional services, especially those with omphalocele and associated chromosomal abnormalities and birth defects.Advertisement
At birth, the newborn's numerous malformations indicate a possible chromosomal abnormality.
Trisomy 13 is confirmed by examining the infant's chromosomal pattern through karyotyping or another procedure.
Because of chromosomal differences between the sexes, some genes are not present in two copies.
Some of these children have other defects such as cardiac anomalies, chromosomal abnormalities, kidney and genital anomalies, and neural tube defects, such as spina bifida.
Klinefelter syndrome is one of the most common chromosomal abnormalities.
There is no treatment available to change chromosomal makeup.
Cri du chat (a French phrase that means "cry of the cat") syndrome is a group of symptoms that result when a piece of chromosomal material is missing (deleted) from a particular region on chromosome 5.
Children born with this chromosomal deletion have a characteristic mewing cat-like cry as infants that is thought to be caused by abnormal development of the larynx (organ in the throat responsible for voice production).
Cri du chat is the result of a chromosome abnormality-a deleted piece of chromosomal material on chromosome 5.
In approximately 10 percent of children with cri du chat, there is a hereditary chromosomal rearrangement that causes the deletion.
The extent of mental retardation and other symptoms depends on the site of the chromosomal deletions, with larger deletions resulting in more serious symptoms.
DiGeorge syndrome is a genetic syndrome most frequently associated with a chromosomal deletion (22q11.2).
Amniocentesis may reveal trisomies or other chromosomal abnormalities.
Careful chromosomal study can reveal abnormalities on chromosome 15 that are consistent with those identified in Angelman's syndrome.
Of all the chromosomal abnormalities that result in spontaneous abortion or miscarriage, Turner's syndrome is the most common, accounting for about 20 percent of all miscarriages.
Because the symptoms caused by the chromosomal abnormality vary somewhat from child to child, the syndrome probably occurs much more often than was previously thought.
While Down syndrome is a chromosomal disorder, a baby is usually identified at birth through observation of a set of common physical characteristics.
Thicker measurements correlate with the possibility of Down syndrome or other chromosomal abnormalities.
Prader-Willi syndrome (PWS) is a genetic condition caused by the absence of chromosomal material from chromosome 15.
The piece of chromosomal material that is deleted contains genes that must be present for normal development.
In fewer than 1 percent of the cases of PWS there is a chromosomal rearrangement in the family that causes the deletion.
This chromosomal rearrangement is called translocation.
The most common cause is chromosomal problems or genetic abnormalities.
The Baby Gender Mentor Home DNA Testing Kit determines gender by tracing the amount of active genetic fetal chromosomal DNA in a sample of your blood.
This procedure enables an obstetrician to determine any chromosomal disorders or open neural tube defects, such as spina bifida, that the unborn fetus may have.
Some individuals have chromosomal abnormalities that make gender identification difficult.
Down syndrome is a chromosomal mutation that can be identified during pregnancy through amniocentesis.
Fragile X syndrome involves chromosomal problems on the X chromosome.
One possible factor is that older women are more likely to conceive babies with chromosomal abnormalities.
Chromosomal abnormalities are the most common cause of first trimester miscarriage.
In fact, studies indicate that more than half of all miscarriages that occur before 12 weeks can be attributed to chromosomal abnormalities.
Combined with the results of other tests, an amnio can give you a good idea of any chromosomal health problems your child could be born with.
Some doctors recommend amnios for any pregnant woman over the age of 35 or when either parent is known to be a carrier of a chromosomal problem.
From the amniotic fluid, lab technicians can determine the sex of the baby as well as other chromosomal abnormalities that indicate a genetic defect.
Most amniocentesis results will turn out normal or, in other words, the test will not detect any chromosomal irregularities and you will go away from your doctor's appointment with a sense of relief.
The blood test given during the first trimester screening is for chromosomal abnormalities in the baby, including Down's Syndrome (trisomy 21), Edwards Syndrome (trisomy 18), skeletal defects, or heart defects.
The amount of fluid behind the baby's neck may indicate an increased risk for a chromosomal abnormality.
The results of the first trimester screening tests, combined with your age, will indicate whether your baby has a high or low risk of chromosomal abnormalities.
Since the results are given as high risk or low risk of chromosomal abnormalities, it does not necessarily mean that your baby has a condition, it just means you need to do further tests.