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cah

cah Sentence Examples

  • The acid renders it available as a manure by converting the calcium phosphate, Ca 3 P 2 O 8, that it contains into the soluble monocalcium salt, CaH 4 P 2 O 8, or "superphosphate."

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  • As previously described, CAH embryos are exposed to excess androgens from the first few weeks, right through until birth.

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  • The acid renders it available as a manure by converting the calcium phosphate, Ca 3 P 2 O 8, that it contains into the soluble monocalcium salt, CaH 4 P 2 O 8, or "superphosphate."

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  • soc. chim., 1902, 27, p. 1141); calcium and strontium similarly form hydrides CaH 2, SrH 2 at a dull red heat (A.

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  • Both sleep-disordered breathing and CAH can be reversed and symptoms improved with the initiation of ventilatory assistance.

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  • Congenital adrenal hyperplasia (CAH) is a genetic disorder characterized by a deficiency in the hormones cortisol and aldosterone and an over-production of the hormone androgen.

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  • CAH is present at birth and affects the sexual development of the child.

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  • Congenital adrenal hyperplasia (CAH) is a form of adrenal insufficiency in which 21-hydroxylase, the enzyme that produces two important adrenal steroid hormones, cortisol and aldosterone, is deficient.

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  • Females with CAH are born with an enlarged clitoris and normal internal reproductive tract structures.

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  • CAH causes abnormal growth for both sexes; those affected will be tall as children but short as adults because of early bone maturation.

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  • In its most severe form, called salt-wasting (or salt-losing) CAH, where there is a total or near total deficiency of the 21-hydroxylase enzyme, a life-threatening adrenal crisis can occur if the disorder is untreated.

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  • There is also a milder form of CAH in which children have partial 21-hydroxylase enzyme deficiencies (simple virilizing form).

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  • Another type of CAH is characterized by only a slight deficiency in production of the 21-hydroxylase enzyme (nonclassic or late-onset form), in which symptoms occurs later in childhood or during young adolescence.

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  • CAH is also called adrenogenital syndrome or 21-hydroxylase deficiency.

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  • CAH, a genetic disorder, is the most common adrenal gland disorder in infants and children, occurring in one in 10,000 total births worldwide.

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  • CAH is related to the deficiency of 21-hydroxylase, an enzyme that is required to transform cholesterol into cortisol.

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  • Various mutations of the 21-hydroxylase gene result in various degrees of CAH (salt-losing form, simple-virilizing form, and the nonclassic form).

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  • Females with severe CAH may be mistaken for males at birth.

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  • If not treated, this form of CAH can result in death within one to six weeks after birth.

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  • In the mild form of CAH, which occurs in late childhood or early adulthood, symptoms include premature development of pubic hair, irregular menstrual periods, unwanted body hair, or severe acne.

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  • Many cases of CAH will be detected at birth, but in milder cases, symptoms may not develop until later, at which time medical care should be obtained.

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  • For children with more severe cases of CAH, regular medical care is necessary to achieve desired treatment results.

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  • CAH is diagnosed by a careful examination of the genitals and blood and urine tests that measure the hormones produced by the adrenal gland.

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  • A number of states in the United States perform a hormonal test (a heel prick blood test) for CAH and other inherited diseases within a few days of birth.

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  • For some forms of CAH, prenatal diagnosis is possible through chronic villus sampling in the first trimester and by measuring certain hormones in the amniotic fluid during the second trimester.

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  • The goal of treatment for CAH is to return the androgen levels to normal.

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  • Treatment results must be monitored carefully, because of large individual variations in enzyme deficiency in children with CAH.

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  • For children with salt-wasting CAH, fludrocortisone (Florinef), which acts like aldosterone (the missing hormone), is also prescribed.

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  • Serum electrolytes must be checked frequently, especially for children with salt-wasting CAH, to assure that normal levels of sodium and potassium are maintained.

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  • CAH patients may have periods of fluctuating hormonal control that lead to increases in the dose of steroids prescribed.

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  • Children with CAH should see a pediatric endocrinologist frequently.

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  • If they require medical treatment, CAH children with the milder form of the disorder are usually effectively treated with hydrocortisone or prednisone.

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  • Females with CAH who have masculine external genitalia require surgery to reconstruct the clitoris and/or vagina.

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  • Adrenalectomy, a surgical procedure to remove the adrenal glands, is a more radical treatment for CAH.

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  • In the early 2000s, it is recommended for CAH children with little or no enzyme activity and can be accomplished by laparoscopy.

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  • Adrenalectomy is followed by hormone therapy, but in lower doses than CAH patients not treated surgically receive.

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  • CAH can be controlled and successfully treated in most patients as long as they remain on drug therapy.

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  • Prenatal therapy, in which a pregnant woman at risk for a second CAH child is given dexamethasone to decrease secretion of androgens by the adrenal glands of the female fetus, has been in use since 1994.

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  • This means that a number of fetuses are exposed to unnecessary steroid treatment in order to prevent the development of male-like genitals in female fetuses with CAH.

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  • Parents with a family history of CAH or who have a child with CAH should seek genetic counseling.

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  • Genetic testing during pregnancy can provide information on the risk of having a child with CAH.

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  • When taking a child with CAH for emergency care, parents are advised to refer to the condition by its full name rather than CAH.

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  • The parents should inform medical personnel if the child has salt-wasting CAH.

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  • It is also recommended that parents have a letter or information prepared concerning CAH and care needed so that this can be given to a new doctors who may treat the child.

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  • Parents should be sensitive to the psychological aspects of the disease and obtain counseling for children with CAH.

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