Biosynthesis sentence example

biosynthesis
  • We are analyzing the mechanisms and programming of antibiotic biosynthesis.
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  • For example, one point at which heme biosynthesis may be controlled is at the first step.
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  • As a result, larger quantities of heme precursors are fed into the biosynthesis pathway to step up heme production.
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  • However, a glitch in the biosynthesis pathway-represented by a defective enzyme-means that heme biosynthesis does not reach completion.
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  • Although there are eight steps in heme biosynthesis, there are only seven types of porphyrias; a defect in ALA synthase activity does not have a corresponding porphyria.
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  • Enzymes involved in heme biosynthesis display subtle, tissue-specific variations; therefore, heme biosynthesis may be impeded in the liver, but normal in the immature red blood cells, or vice versa.
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  • Porphyrias affecting heme biosynthesis in the liver were referred to as hepatic porphyrias.
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  • Porphyrias that affect heme biosynthesis in immature red blood cells were referred to as erythropoietic porphyries.
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  • Hepatoerythopoietic porphyria (HEP) affects heme biosynthesis in both the liver and the bone marrow.
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  • The underlying cause of all porphyrias is a defective enzyme important to the heme biosynthesis pathway.
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  • Owing to deficient ferrochelatase, the last step in the heme biosynthesis pathway-the insertion of an iron atom into a porphyrin molecule-cannot be completed.
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  • Making this determination yields a strong indicator of which enzyme in the heme biosynthesis pathway is defective; which, in turn, allows a diagnosis of the particular type of porphyria.
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  • Other biochemical tests rely on the fact that heme precursors become less soluble in water (able to be dissolved in water) as they progress further through the heme biosynthesis pathway.
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  • It exerts its effects directly in inflamed tissues underlying the site of application, mainly by inhibiting prostaglandin biosynthesis.
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  • However this is not the case for the chloroplast complex which plays a distinct role in supplying acetyl CoA for fatty acid biosynthesis.
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  • Returning to the more orthodox version of the cannabinoid biosynthesis, the role of ultraviolet light should be reemphasized.
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  • Inhibition of glycolipid biosynthesis does not reverse multidrug resistance in cancer.
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  • Further analysis of the microarray data has suggested roles for these regulatory elements other than in the control of flagellar biosynthesis.
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  • One main focus of our research is on enzymes involved in tetrapyrrole biosynthesis.
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  • Although the pathway for lignin biosynthesis was outlined many years ago, important basic features are still poorly understood.
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  • An area of research for several years has been proteins and enzymes involved in lipid biosynthesis.
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  • Indeed, luteolin also efficiently blocked the insulin effect on cholesterol biosynthesis.
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  • These results are in conformity with the lack of genetic regulation of amino acid biosynthesis in Streptomyces.
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  • Remarkably neither route for SA biosynthesis is completely elucidated.
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  • Many of the novel predicted genes are associated with surface polysaccharide, flagellar biosynthesis and modification in addition to hypothetical genes.
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  • This enzyme is believed to be involved in the biosynthesis of isoleucine in methanogens and possibly other species lacking threonine dehydratase.
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  • It is a xanthine oxidase inhibitor and accordingly inhibits the biosynthesis of uric acid.
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  • Biosynthesis of heme is a multistep process that begins with simple molecules and ends with a large, complex heme molecule.
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  • Owing to a defect in one of the enzymes of the heme biosynthesis pathway, protoporphyrins or porphyrins (heme precursors) are prevented from proceeding further along the pathway.
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  • Specific symptoms depend on the point at which heme biosynthesis is blocked and which precursors accumulate.
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  • Heme is produced in several tissues in the body, but its primary biosynthesis sites are the liver and the bone marrow.
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  • Much of the heme biosynthesis pathway is dedicated to constructing the porphyrin molecule.
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  • An iron atom is placed at its center point in the last step of heme biosynthesis.
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  • The control of heme biosynthesis is complex.
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  • Hematin seems to work by signaling the pathway of heme biosynthesis to slow production of precursors.
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  • It causes heme biosynthesis to decrease, preventing the further accumulation of heme precursors.
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  • Additional tests include plasmalogen biosynthesis potential.
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