The benefits of goldenseal are enhanced when it is combined in formulas with multiple herbs and when taken as a whole herb rather than berberine extract, the active ingredient and the one currently being scrutinized in research studies.
According to the National Center for Complimentary and Alternative Medicine (NCCAM), berberine shows some promise fighting infections, especially eye infections and infectious diarrhea.
The government currently funds several studies on goldenseal and berberine, but results aren't in yet.
One compound found in goldenseal that has been studied is called berberine.
His chief researches deal with the polymethylene compounds, the alkaloids, in particular hydrastine and berberine, and the camphors and terpenes.
BERBERINE, C 20 H 17 N0 4, an alkaloid occurring together with the alkaloids oxyacanthine C18H19N03, berbamine C18H19N03, hydrastine C21H21N06, and canadine C 20 H 21 N0 4, in Berberis vulgaris; it also occurs in other plants, Berberis aristata, B.