B-cells sentence example

b-cells
  • autoantibodylls could then induce B cells to produce autoantibodies against self antigens.
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  • Islet tissue also contains a cells which manufacture the antagonistic hormone glucagon, but these a cells rely on the b cells for guidance.
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  • The underlying pathophysiology seems to be that E.B.V. specifically infects B cells and then incites a T cell response (atypical lymphocytes ).
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  • We teach undergraduate students doing BSc projects and clinical rheumatology; also running specialist modules for those interested in B cells.
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  • The B cells protect the body by making antibodies, which are proteins that can attach to the surfaces of bacteria and viruses.
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  • The two main groups are the B cells that have antibody molecules on their surface and T cells that destroy antigens.
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  • In A-T children, B-cell responses are very weak, and levels of immunoglobulins, the proteins that B-cells make to fight infection by specific recognition of invading organisms, may also be low.
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  • When introduced into the body, the antigens stimulate the immune system response by instructing B cells to produce antibodies, with assistance from T-cells.
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  • Immunoglobulins are made by white blood cells known as B cells (B lymphocytes).
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  • Any disease that harms the development or function of B cells will, therefore, affect the production of immunoglobulin antibodies.
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  • Defect results in absence or reduced numbers of B cells that do not mature and perform normal function.
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  • Mature B cells are capable of making antibodies and developing memory, a feature in which the B cell will rapidly recognize and respond to an infectious agent the next time it is encountered.
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  • It is believed to be caused by a defect in the development of T helper cells (cells that recognize foreign antigens and activate T and B cells in an immune response).
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  • Selective IgA deficiency is an inherited disease characterized by a failure of B cells to switch from making IgM to IgA antibodies.
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  • IgG deficiency with hyper-IgM is a disorder that results when B-cells fail to switch from making IgM to IgG.
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  • Defects can occur at two main points in the development of B-cells.
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  • First, B cells can fail to develop into antibody-producing cells.
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  • Secondly, B cells can fail to make a particular type of antibody or fail to switch classes during maturation.
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  • Initially, when B cells start making antibodies for the first time, they make IgM.
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  • Although the total IgG level may be normal, the imbalance in the types of IgG antibodies makes the B cells unprepared to fight all types of infection.
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  • B-cell lymphomas-Non-Hodgkin's lymphomas that arise from B cells.
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  • This defect is not associated with the immunoglobulins themselves, but rather with the B cells in the bloodstream that ordinarily secrete the immunoglobulins.
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  • If Btk is missing or defective, the B cells cannot mature and cannot produce immunoglobulins.
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  • This defect blocks B cells from maturing.
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  • Only mature B cells produce immunoglobulins.
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  • Bruton's agammaglobulinemia tyrosine kinase (Btk)-An enzyme vital for the maturation of B cells.
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  • In other words, the T and B cells are important in the immunity that vaccination promotes.
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