These nerve impulses then stimulate the end of an axon to release chemicals called neurotransmitters that spread out and communicate with the dendrites of neighboring nerve cells.
A nerve can be likened to an electrical wire, in which the wire part is the axon of the nerve and the insulation surrounding it is the myelin sheath.
Children who have problems with the myelin have CMT type 1 and children who have abnormalities of the axon have CMT type 2.
The job of this gene is to make the layers of myelin stick together as they are wrapped around the axon.
On the other hand, in some neurons, after severance of the axon from the rest of the cell (spinal motor cell), the whole nerve cell as well as the severed axon degenerates, and may eventually die and be removed.
In the severed axon the degeneration is first evident in a breaking down of the naked nerve filaments of the motor end plate.
This indicates that the conjunction between the conducting substance of the dendrons and that of the axon can be effected without the intermediation of the cell body.
A little later the breaking down of the whole axon, both axis cylinder and myelin sheath alike, seems to occur simultaneously throughout its entire length distal to the place of severance.
The neuron is described as having a cell body or perikaryon from which the cell branches - dendrites and axon - extend, and it is this perikaryon which, as its name implies, muscle produces lactic acids during activity, it has been suggested that acids are among the "fatigue substances" with which muscle poisons itself when deprived of circulating blood.