Agammaglobulinemia sentence example

agammaglobulinemia
  • X-linked agammaglobulinemia is an inherited disease stemming from a defect on the X chromosome, consequently affecting more males than females.
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  • All classes of immunoglobulin antibodies are decreased in agammaglobulinemia.
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  • Immunoglobulin heavy chain deletion, a form of agammaglobulinemia, is a genetic disorder in which part of the antibody molecule is absent.
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  • X-linked agammaglobulinemia is an example of this disease.
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  • The congenital immunodeficiency disorder, Bruton's agammaglobulinemia, also known as X-linked agammaglobulinemia, results in a decrease or absence of B lymphocytes and, therefore, a decreased ability to make antibodies.
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  • Patients with Bruton's agammaglobulinemia must be given periodic infusions of pooled immunoglobulin from multiple donors.
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  • People with Bruton's agammaglobulinemia who are given IVIG infusions generally live into their 30s or 40s.
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  • Bruton's agammaglobulinemia is a disorder that is present at birth (congenital) and is characterized by low or completely absent levels of immunoglobulins in the bloodstream.
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  • Bruton's agammaglobulinemia is also known as X-linked agammaglobulinemia (XLA).
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  • The maturation process depends on an enzyme called Bruton's agammaglobulinemia tyrosine kinase (Btk).
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  • Bruton's agammaglobulinemia tyrosine kinase (Btk)-An enzyme vital for the maturation of B cells.
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