In one mode of adenovirus infection (called lytic infection because it destroys large numbers of cells), adenoviruses kill healthy cells and replicate up to 1 million new viruses per cell killed, of which 1 to 5 percent are infectious.
As much as 51 percent of all hemorrhagic cystitis (inflammation of the bladder and of the tubes that carry urine to the bladder from the kidneys) in American and Japanese children can be attributed to adenovirus infection.
In addition to a sore throat, symptoms that accompany an adenovirus infection include cough, runny nose, white bumps on the tonsils and throat, mild diarrhea, vomiting, and a rash.
A vaccine containing live adenovirus types 4 and 7 has been used to control disease in military recruits, but it is not recommended or available for civilian use.
Viruses cause the majority of pneumonias in young children, especially respiratory syncytial virus, parainfluenza and influenza viruses, and adenovirus.
Infection with an adenovirus, however, may also cause a significant amount of pus-like discharge and a scratchy, foreign-body-sensation in the eye.
Practicing good personal hygiene and avoiding contact with people with infectious illnesses can reduce the risk of developing adenovirus infection.
In children with gastroenteritis caused by the adenovirus, symptoms may include diarrhea, fever, nausea, vomiting, and respiratory symptoms.
Symptoms common to respiratory illnesses caused by adenovirus infection include cough, fever, runny nose, sore throat, and watery eyes.
Although symptoms may suggest the presence of adenovirus, distinguishing these infections from other viruses can be difficult.