Acridine sentence example

acridine
  • Similarly a CH group may be replaced by a nitrogen atom with the production of compounds of similar stability; thus benzene gives pyridine, naphthalene gives quinoline and isoquinoline; anthracene gives acridine and a and 3 anthrapyridines.
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  • The quinonoid structure of many coloured compounds has been proved experimentally, as, for example, by Hewitt for the benzene-azo-phenols, and Hantzsch for triaminotriphenyl methane and acridine derivatives; but, at the same time, many substances cannot be so explained.
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  • This oscillation may be represented in the case of acridine and fluorescein as This theory brings the property of fluorescence into relation with that of colour; the forms which cause fluorescence being the coloured modifications: ortho-quinonoid in the case of acridine, paraquinonoid in the case of fluorescein.
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  • This tautomerism may be of a twofold nature :-(I) it may involve the mere oscillation of linkages, as in acridine; or (2) it may involve the oscillation of atoms, as in fluorescein.
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  • It may be separated by shaking out with dilute sulphuric acid, and then precipitating the sulphuric acid solution with potassium bichromate, the resulting acridine bichromate being decomposed by ammonia.
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  • Many synthetic processes are known for the production of acridine and its derivatives.
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  • Acridine and its homologues are very stable compounds of feebly basic character.
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  • Acridine crystallizes in needles which melt at 110° C. It is characterized by its irritating action on the skin, and by the blue fluorescence shown by solutions of its salts.
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  • Numerous derivatives of acridine are known and may be prepared by methods analogous to those used for the formation of the parent base.
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  • Many derivatives are known, thus ortho-amino-benzophenone, melting at 106° C., can be obtained by reduction of the corresponding nitro compound; it condenses under the influence of heated lead monoxide to an acridine derivative and with acetone in presence of caustic soda it gives a quinoline.
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  • The next step was to use a fluorochrome (fluorescent stain) which is a powerful nuclear stain, namely, Acridine Orange.
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  • Acridine crystallizes in needles which melt at 110° C. It is characterized by its irritating action on the skin, and by the blue fluorescence shown by solutions of its salts.
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  • Many derivatives are known, thus ortho-amino-benzophenone, melting at 106° C., can be obtained by reduction of the corresponding nitro compound; it condenses under the influence of heated lead monoxide to an acridine derivative and with acetone in presence of caustic soda it gives a quinoline.
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