Aconitine sentence example
- Aconitine (C33H45N013, according to Dunstan; C34H47NOH, according to Freund) is a crystalline base, soluble in alcohol, but very sparingly in water; its alcoholic solution is dextrorotatory, but its salts are laevorotatory.
- The usual test for solutions of aconitine consists in slight acidulation with acetic acid and addition of potassium permanganate, which causes the formation of a red crystalline precipitate.
- The action of aconitine on the circulation is due to an initial stimulation of the cardio-inhibitory centre in the medulla oblongata (at the root of the vagus nerves), and later to a directly toxic influence on the nerve-ganglia and muscular fibres of the heart itself.
- The best method of application is by rubbing in a small quantity of the aconitine ointment until numbness is felt, but the costliness of this preparation causes the use of the aconite liniment to be commonly resorted to.
- Aconitine, delphinine and many of their derivatives have a very widespread depressing action on muscle and nerve.Advertisement