The drug must be at once withheld if haemorrhages (subcutaneous, retinal, &c.) are observed.
These crystals are extremely resistant to absorption, are found in old blood clots, and have been known to persist in old cerebral haemorrhages after many years.
A widespread toxic action is indicated by the lesions found - cloudy swelling, which may be followed by fatty degeneration, in internal organs, capillary haemorrhages, &c. In septicaemia.
(Many such changes are usually grouped together under the heading of " inflammation " of varying degree--acute, subacute and chronic.) Degeneration and death of cells, haemorrhages, serous and fibrinous exudations, leucocyte emigration, proliferation of connective tissue and other cells, may be mentioned as some of the fundamental changes.
The exhausting pain, the serious haemorrhages, and the abdominal septicity associated with a repulsive odour and the absorption of toxic products, which are the chief and ultimately fatal symptoms of that disease, are all directly combated by the administration of oil of turpentine.
Submucous haemorrhages are usually present, but perforation is rare.