After large doses haematuria has been observed in a few cases.
In Egypt 30% of the natives are affected by haematuria which arises from congestion of the bladder consequent upon the attacks of this animal.
Haematuria means passage of blood with the urine.
Quinine is much less efficacious in the treatment of post-malarial symptoms, such as neuralgia and haematuria, when no parasites can be detected in the blood.
It must not be used to check haemorrhage from the kidneys (haematuria) owing to its irritant action on those organs, but in haemoptysis (haemorrhage from the lungs) it is often an invaluable remedy.