Combined with opium it is an efficient remedy in diabetes insipidus.
The first scientific attempt to employ portions of raw organs in the treatment of disease was made by Lauder Brunton in diabetes in 1873, sixteen years before Brown-Sequard's paper on the effect of testicular juice.
It is said to be increased in saccharine diabetes and to be greatly diminished in starvation and wasting diseases.
In diabetes this organ seems to play a part which is not yet precisely determined; and one fell disease at least has been traced to a violent access of inflammation of this organ, caused perhaps by entry of foreign matters into its duct.
From considering the nature of diabetes, he had come to the conclusion that many cases were due to imperfect oxidation of sugar in the body; that this oxidation was normally carried out by a ferment in the muscles, and that probably the disease was in some cases dependent upon absence of the ferment.
In the animal kingdom, also, it is very widely distributed, being sometimes a normal and sometimes a pathological constituent of the fluids and tissues; in particular, it is present in large amount in the urine of those suffering from diabetes, and may be present in nearly all the body fluids.
In diabetes mellitus, in which there is marked derangement in metabolism, extreme fatty changes are occasionally found in the organs, and the blood may be loaded with fat globules.
By the revelations of this instrument not only have the diseases of the eye been illuminated, but much light has been thrown also upon the part of the eye in more general maladies; as, for instance, in syphilis, in diabetes, in kidney diseases, and in diseases of the brain - F.
In true diabetes, which probably originates in the central nervous system, or in disease of the pancreas, as well as in the glycosuria common in gouty patients, sugar in every form should be entirely forbidden, and starchy food restricted to within narrow limits.
But the change was unavailing, and after a lingering illness, in which he suffered first from diabetes, then from Bright's disease, complicated by dropsy, he died in Paris on the 2nd of October 1853.
Opium is often preferred to morphine in cases of diabetes, where prolonged administration is required.
In some skin diseases such as psoriasis, chronic eczema and acne indurata, phosphorus is very useful, and cases of diabetes mellitus and lymphadenoma have improved under some of its compounds.
But some parts of Willis's works, such as his descriptions of nervous diseases, and his account (the earliest) of diabetes, are classical contributions to scientific medicine.
This is apt to be met with in oldish persons with diseased vessels and feeble heart-action, especially if the blood is rendered less nutritious by the presence of diabetes or of kidney disease.
The same year, a technique for treating diabetes, insulin therapy, was developed.