Pain may be stopped by removing the cause of irritation, as, for example, by the extraction of a carious tooth or by rendering the nerveendings insensitive to irritation, as by the application of cocaine; by preventing its transmission along the spinal cord by antipyrin, phenacetin, acetanilide, cocaine, &c.; or by dulling the perceptive centre in the brain by means of opium or its alkaloids, by anaesthetics, and probably also, to a certain extent, by antipyrin and its congeners.
But by the addition of some antiseptic to the ointment its defensive action would be converted from passive to active, and its power to prevent infection would become greater; and if inflammation had already set up in the skin, the addition of opium, belladonna, or cocaine would lessen local pain; and an astringent, either metallic or organic, would restrain inflammation and accelerate repair.
Homologues of cocaine - ethylbenzoylecgonine, &c. - have been prepared; they closely resemble natural cocaine.
Cinnamyl cocaine is cinnamylmethylecgonine, i.e.
Irritation is lessened by lotions containing substances that will diminish irritability of the nerve-endings and skin, such as carbolic acid, hydrocyanic acid, morphine or opium, cocaine, belladonna or atropine.
Cocaine in which the benzoyl group is replaced by the cinnamyl group. aand 3-truxillines, named from their isolation from a coca of Truxillo (Peru), are two isomeric alkaloids which hydrolyse to ecgonine, methyl alcohol, and two isomeric acids, the truxillic acids, C18H1604.
The manufacturing industries of Peru are confined chiefly to the treatment of agricultural and mineral products - the manufacture of sugar and rum from sugar cane, textiles from cotton and wool, wine and spirits from grapes, cigars and cigarettes from tobacco, chocolate from cacao, kerosene and benzine from crude petroleum, cocaine from coca, and refined metals from their ores.
Cocaine is benzoylmethyl ecgonine.
And yet, Yancey had mentioned cocaine in his telephone conversation.
The exports consist of cotton, sugar, cocaine, hides and skins, rubber and other forest products, wool, guano and mineral products.
It is associated with many other alkaloids: cinnamyl cocaine, C19H23N04; a-truxilline (C19H23N04) 2; /3-truxilline, (C19H23N04) 2; benzoylecgonine, C 16 H 19 NO 2 j tropa-cocaine, C15H19N02; hygrine, C 8 H 15 NO; cuscohygrine, C13H24N02.
The conversion of the mixture obtained by extracting coca-leaves into cocaine is effected by saponifying the esters into ecgonine and the respective acids, and then benzoylating and methylating the ecgonine.
It is obtained by hydrolysing cocaine with acids or alkalis, and crystallizes with one molecule of water, the crystals melting at 198° to 199° C. It is laevo-rotatory, and on warming with alkalis gives iso-ecgonine, which is dextro-rotatory.
Piperine, conine, atropine, belladonine, cocaine, hyoscyamine and nicotine have been already synthesized; the constitution of several others requires confirmation, while there remain many important alkaloids - quinine, morphine, strychnine, &c. - whose constitution remains unknown.
Cocaine is the active principle of the coca leaf, which is chewed as a stimulant-narcotic in Peru and Bolivia.
The chief action of cocaine from a practical point of view is its power of paralysing the terminations of sensory nerves.
Cocaine is also derived from coca leaves, and a considerably quantity of the drug is exported.
Atropine; cocaine; hygrine; ecgonine; pelletierine.
Opium, cocaine or cerium oxalate.
Maybe they found cocaine on her and she needed twenty-five thousand to get out of jail.
Of cocaine) may replace that of opium-smoking in China.