The bearing of this fact on cases of cardiac dilatation is evident.
The essential point here to be added is that death takes place from combined cardiac and respiratory failure.
Summed up, its action is that of an irritant, and a cardiac and nervous depressant.
Over the right part the mucous membrane has a greyish-red colour and a velvety appearance, and contains numerous peptic glands, which are wanting in the cardiac portion.
When the growth is at the cardiac end of the stomach, blocking the gullet and causing slow starvation, the abdomen may advisedly be opened, and, the stomach having been fixed to the surface-wound, a permanent opening may be arranged for the introduction of an adequate amount of food.
Ten to twenty minims of ether, subcutaneously injected, constitute perhaps the most rapid and powerful cardiac stimulant known, and are often employed for this purpose in cases of syncope under anaesthesia.
All potassium salts if taken in large doses are cardiac depressants, they also depress the nervous system, especially the brain and spinal cord.
The cardiac portion of the complex stomach has a horny layer, and there is a caecum.
Of the hydrochloride may stimulate the cardiac action.
Digitalis contains four important glucosides, of which three are cardiac stimulants.
Digitonin, on the other hand, is a cardiac depressant, and has been found to be identical with saponin, the chief constituent of senega root.
The systole is not altered in length, but the diastole is very much prolonged, and since this is the period not only of cardiac rest but also of cardiac "feeding" - the coronary vessels being compressed and occluded during systole - the result is greatly to benefit the nutrition of the cardiac muscle.
This formula includes the vast majority of cardiac cases.
The uses of atropine in cardiac affections are still obscure and dubious.
It can only be laid down that the drug is a valuable though temporary stimulant in emergencies, and that its use as a plaster or internally often relieves cardiac pain.
The medieval Jews also held that there is a cardiac demon in wine which takes possession of drunken men; and the Mahommedan prohibition of wine-drinking is based on a similar superstition.
The drug is not a true specific, as quinine is for malaria, since it rarely, if ever, prevents the cardiac damage usually done by rheumatic fever; but it entirely removes the agonizing pain, shortly after its administration, and, an hour or two later, brings down the temperature to normal.
Avellanarius, the common dormouse, distinguished by the cylindrical bushy tail, and thickened glandular walls of the cardiac extremity of the oesophagus; thirdly, Eliomys, containing several species, with tufted and doubly vaned tails, simple stomachs and smaller molar teeth, having concave crowns and faintly marked enamel-folds; and lastly, the African Graphiurus, represented by several species, with short cylindrical tails ending in a pencil of hairs, and very small molars almost without trace of enamel-folds.
Not only is the respiratory centre stimulated but the cardiac centre is acted upon both directly by the drug and indirectly for a time by the enormous rise in blood pressure due to the contraction of the arterioles all over the body.
This is due to a very definite influence upon the different portions of the cardiac cycle.
The cardiac contractions become irregular, the ventricle assumes curious shapes - "hour-glass," &c. - becomes very pale and bloodless, and finally the heart stops in a state of spasm, which shortly afterwards becomes rigor-mortis.
Clinically it is to be observed that the drug is cumulative, being very slowly excreted, and that after it has been taken for some time the pulse may become irregular, the blood-pressure low, and the cardiac pulsations rapid and feeble.
The initial action of digitalis is a stimulation of the cardiac terminals of the vagus nerves, so that the heart's action is slowed.
Thereafter follows the most important effect of the drug, which is a direct stimulation of the cardiac muscle.
This can be proved to occur in a heart so embryonic that no nerves can be recognized in it, and in portions of cardiac muscle that contain neither nervecells nor nerve-fibres.
Alcohol and cardiac stimulants may be required to prevent heart failure.
As it does not depress the heart when used in medicinal doses, it may be given to patients suffering from cardiac disease.
When this continues for a length of time it tends by itself to cause deterioration of the blood-vessels and leads to death either by cerebral apoplexy or by cardiac failure.
Rest in bed should be insisted upon for a longer time than appears actually required, because acute rheumatism tends to bring on cardiac changes, and is more likely to do this when the heart is excited than when the patient is kept at rest.
Exercises, passive and active, are also used in diseases of the joints, as well as massage and baths, but exercises and training are even more important in cases of cardiac disease.
It is a powerful cardiac depressant, diminishing both the force and frequency of the heart's beat.
In most Decapods the " stomach " or dilated portion of the fore-gut is divided into two chambers, a large anterior " cardiac " and a smaller posterior " pyloric."
Use hot bottles and stimulants, especially trying to counteract the cardiac depression by atropine, caffeine, strophanthin, &c.
It used to be stated that these drugs are marked cardiac depressants; and the heart being invariably implicated in rheumatic fever, it is supposed that these drugs must be given with great caution.
It has now been established that, provided the kidneys be healthy, natural salicylic acid, sodium salicylate prepared from the natural acid, and salicin, are not cardiac depressants.
In twenty-four hours, without any toxic symptoms. The artificial acid and its salt contain ortho-, paraand meta-cresotic acids, which are cardiac depressants.
Whilst absolutely contra-indicated in all cases of valvular disease, it is of value in cases of cardiac hypertrophy with over-action.
Nitroglycerin is valuable as a preventive in cases of cardiac pain, such as angina pectoris, and it is also used in other conditions where it is desirable to reduce the arterial tension.
The beaver, glandular masses are attached to and open into the cardiac or pyloric pouches.
Later in its action, the drug depresses the intra-cardiac motor ganglia, causing prolongation of diastole and finally arrest of the heart in dilatation.
Added to the greater force of cardiac contraction is a permanent tonic contraction of the organ, so that its internal capacity is reduced.
A certain consequence of its use is to cause or increase cardiac hypertrophy - a condition which has its own dangers and ultimately disastrous consequences, and must never be provoked beyond the positive needs of the case.
The respiratory centre is similarly stimulated, so that atropine must be regarded as a temporary but efficient respiratory and cardiac stimulant.
Thiourea and many of its unsymmetrical derivatives have marked physiological action; thiourea causes a slowing of the pulse and respiration, cardiac failure, and death in convulsions; phenyl-, ethyland acetyl-thiourea are actively toxic. The most important derivative pharmacologically is allyl-thiourea, also known as thiosinamine or rhodallin, NH2 CS NH CH2 CH:CH2.
Beri-beri is a dietetic deficiency disease which manifests itself by cardiac weakness with shortness of breath, swelling of the legs and peripheral neuritis with numbness of the limbs and weakness.
The stomach of the horse is simple in its external form, with a largely developed right cul de sac, and is a good deal curved on itself, so that the cardiac and pyloric orifices are brought near together.
The tail is long and in some cases prehensile; the first hind-toe may be either large, small or absent; the dentition usually includes three pairs of upper and one of lower incisors, and six or seven pairs of cheekteeth in each jaw; the stomach is either simple or sadculated, without a cardiac gland; and there are four teats.
In the region of the neck lateral strands pass through the transverse canal of the cervical vertebrae; but from the thoracic region onwards, where the cardiac branch to the heart is given off, each strand is double and the basal ganglia are successively connected with the next by a branch which runs ventrally over the capitulum of the rib, and by another which passes directly through the foramen or space formed between capitulum and tuberculum.