It is obtained by the oxidation of xanthene (methylene diphenylene oxide) with chromic acid; by the action of phosphorus oxychloride on disodium salicylate; by heating 2 2'-dioxybenzophenone with concentrated sulphuric acid; by distilling fluoran with lime; by the oxidation of xanthydrol (R.
OH, whilst a strong reducing agent like hydriodic acid converts it into xanthene, the group >CO becoming > CH.
Xanthene, C13H100, may be synthesized by condensing phenol with ortho-cresol in the presence of aluminium chloride.
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