1547), Ottavio (1586), Alessandro (1592), Ranuccio I.
But in 1549 Pier Luigi was assassinated by his outraged subjects, and the emperor thereupon claimed the two duchies for his son-in-law Ottavio Farnese, Paul's grandson.
The disobedience of his favourite Ottavio hastened the death of the old pope (Nov.
As an adherent of the emperor he suffered in consequence of imperial reverses, and was forced to confirm Parma to Ottavio Farnese, the ally of France (1552).
It was sold in 1623, and in 1634 given to Ottavio Piccolomini; finally, after many changes of ownership, the castle and titular lordship came in 1840 to the princes of Schaumburg-Lippe.
Ottavio, the second son (1521-1586), married Margaret, the natural daughter of Charles V.
Ottavio had been made lord of Camerino in 1540, but he gave up that fief when his father became duke of Parma.
When, on the murder of the latter in 1547, Piacenza was occupied by the imperialists, Paul determined to make an effort to regain the city; he set aside Ottavio's claims to the succession of Parma, where he appointed a papal legate, giving him back Camerino in exchange, and then claimed Piacenza of the emperor, not for the Farnesi, but for the Church.
But Ottavio would not be put off; he attempted to seize Parma by force, and having failed, entered into negotiations with Gonzaga.
During the interregnum that followed Ottavio again tried to induce the governor of Parma to give up the city to him, but met with no better success; however, on the election of Giovan Maria Ciocchi (Julius III.) the duchy was conferred on him (1551).
This did not end his quarrel with the emperor, for Gonzaga refused to give up Piacenza and even threatened to occupy Parma, so that Ottavio was driven into the arms of France.
He was the son of Ottavio Farnese, duke of Parma, and Margaret of Austria, natural daughter of Charles V.